Luxury Panama Canal Cruises 2025 - Premium Cruise Lines

4.9/5 ⭐Google 600+ Reviews | A+ Better Business Bureau

*Rates and offers are per person, in US Dollars, based on double occupancy, capacity controlled, subject to availability and confirmation, and may change without notice. Government taxes and fees are included. Rates and offers are available for select dates and categories only. Additional restrictions may apply. Call 1-800-377-9383 for full terms and conditions.

Luxury Panama Canal Cruises

Upcoming Luxury Panama Canal Cruises

More to Explore

Cruise Deals - delivered to your inbox

7-night Costa Rica & Panama Canal Cruise

38-night Panama Canal Passage & Pacific Crossing Cruise

22-night Atlantic Crossing & Panama Canal Passage Cruise

17-night A Tale Of Two Seas Voyage

$7,399

18-night Star Collector: Reefs & Rainforests: The Caribbean, Colombia, Panama & Costa Rica via the Panama Canal Cruise

22-night Palms To Andean Peaks Voyage

$5,699

14-night Panama Canal & Central America Cruise

$4,999

20-night Star Collector: Central America & The Caribbean: Cloudforest Coastlines, Canal Locks & Calypso Concerts Cruise

10-night Classic Panama Canal Passage Cruise

$3,699

27-night Caribbean, Panama Canal Passage & Hawaii Cruise

16-night Southern Caribbean Beauty Cruise

46-night Panama Canal Passage & Pacific Crossing Cruise

12-night Pacific Pathways Voyage

$3,699

10-night Caribbean & Panama Canal Passage Cruise

$6,709

11-night Monteverde Cloud Forest & Arenal Volcano Cruise/Land Package

30-night Caribbean Shores to Rio's Marvels Cruise

7-night Costa Rica & Panama Canal Cruise

12-night Pacific Pathways Voyage

$4,599

42-night Panama Canal & Hawaiian Holiday Cruise

13-night Star Collector: Coffee, Canal & Callaloo: Central America, Colombia & The Caribbean Cruise

29-night Caribbean Gems & Panama Canal Cruise

54-night Odyssey To World's End Voyage

$13,799

22-night Panama Canal Passage Cruise

$9,924

42-night Iconic Isles To Icebergs Voyage

$10,599

10-night Classic Panama Canal Passage Cruise

$3,299

Luxury Panama Canal Cruises

Upcoming Luxury Panama Canal Cruises

More to Explore

Destinations

Departure Ports

Cruise Lines

Deals

Land Vacations

All About Cruising

7-night Costa Rica & Panama Canal Cruise

38-night Panama Canal Passage & Pacific Crossing Cruise

22-night Atlantic Crossing & Panama Canal Passage Cruise

17-night A Tale Of Two Seas Voyage

$7,399

18-night Star Collector: Reefs & Rainforests: The Caribbean, Colombia, Panama & Costa Rica via the Panama Canal Cruise

22-night Palms To Andean Peaks Voyage

$5,699

14-night Panama Canal & Central America Cruise

$4,999

20-night Star Collector: Central America & The Caribbean: Cloudforest Coastlines, Canal Locks & Calypso Concerts Cruise

10-night Classic Panama Canal Passage Cruise

$3,699

27-night Caribbean, Panama Canal Passage & Hawaii Cruise

16-night Southern Caribbean Beauty Cruise

46-night Panama Canal Passage & Pacific Crossing Cruise

12-night Pacific Pathways Voyage

$3,699

10-night Caribbean & Panama Canal Passage Cruise

$6,709

11-night Monteverde Cloud Forest & Arenal Volcano Cruise/Land Package

30-night Caribbean Shores to Rio's Marvels Cruise

7-night Costa Rica & Panama Canal Cruise

12-night Pacific Pathways Voyage

$4,599

42-night Panama Canal & Hawaiian Holiday Cruise

13-night Star Collector: Coffee, Canal & Callaloo: Central America, Colombia & The Caribbean Cruise

29-night Caribbean Gems & Panama Canal Cruise

54-night Odyssey To World's End Voyage

$13,799

22-night Panama Canal Passage Cruise

$9,924

42-night Iconic Isles To Icebergs Voyage

$10,599

10-night Classic Panama Canal Passage Cruise

$3,299