From the Amazon to the Andes, South American river cruises provide a unique journey through rainforests, cultures, and landscapes.
4.9/5 ⭐Google 600+ Reviews | A+ Better Business Bureau
Aboard
AmaMelodia
From
Cartagena, Colombia
32 Sailings
Jan 28, 2026 - Jun 16, 2027
Published prices from
per person*
taxes & fees included
Aboard
AmaMelodia
From
Cartagena, Colombia
1 Sailing
Dec 17, 2025
Published prices from
per person*
taxes & fees included
Aboard
AmaMelodia
From
Barranquilla, Colombia
1 Sailing
Apr 29, 2026
Aboard
AmaMelodia
From
Medellín, Colombia
1 Sailing
Dec 21, 2025
Aboard
AmaMelodia
From
Cartagena, Colombia
1 Sailing
Dec 17, 2025
Aboard
AmaMagdalena
From
Barranquilla, Colombia
14 Sailings
Dec 27, 2025 - Jun 26, 2027
Published prices from
per person*
taxes & fees included
Aboard
AmaMelodia
From
Cartagena, Colombia
29 Sailings
Jan 26, 2026 - Jun 14, 2027
Published prices from
per person*
taxes & fees included
Aboard
AmaMelodia
From
Medellín, Colombia
11 Sailings
Jan 8 - Jun 11, 2027
Published prices from
per person*
taxes & fees included
Aboard
AmaMelodia
From
Medellín, Colombia
32 Sailings
Jan 18, 2026 - Jun 6, 2027
Published prices from
per person*
taxes & fees included
Aboard
AmaMagdalena
From
Barranquilla, Colombia
23 Sailings
Jan 10 - Dec 26, 2026
Published prices from
per person*
taxes & fees included
Aboard
AmaMagdalena
From
Medellín, Colombia
37 Sailings
Dec 24, 2025 - Jun 23, 2027
Published prices from
per person*
taxes & fees included
Aboard
AmaMagdalena
From
Medellín, Colombia
29 Sailings
Jan 12, 2026 - May 31, 2027
Aboard
Delfin III
From
Lima, Peru
30 Sailings
Jan 2, 2026 - Nov 5, 2027
Published prices from
per person*
taxes & fees included
Aboard
Aria Amazon
From
Lima, Peru
22 Sailings
Jan 14, 2026 - Dec 1, 2027
Published prices from
per person*
taxes & fees included
Our expert consultants and customer service teams are standing by to help with all of your cruising needs.
I was having some trouble finding the right cruise for the right price as a single traveler, but thanks to [our Cruise Expert] I was able to find it with Cruise Web. Thank you very much [our Cruise Expert]!
Camille G.
We have worked with [our Cruise Expert] several times and she makes it so easy and a pleasure to work with. She is very knowledgeable.
Linda F.
[Our Cruise Expert] was informative and very pleasant to work with. I'm not familiar with booking travel online and he made my experience pleasant.
Sharon E.
I would like to mention that for many years I really appreciate to have [our Cruise Expert] taking care of my cruises in the states. So, i'm glad to give five stars for him
Rudi D.
I am working with [our Cruise Expert] as my travel agent...he has been very helpful...he is very informative and knowledgeable about the places that I want to go on my Cruise....I would use [our Cruise Expert] and Cruise Web again to book another cruise...thank you...
Priscilla B.
[Our Cruise Expert] does an exceptional job of planning (with you) and coordinating a trip of your dreams! I can't wait to get started on the next one.
Sheralyn H.
Great working with [our Cruise Expert]! He was a tremendous help and steered us in the right direction every time! Helped us make memories for a lifetime!
Wendy F.
[Our Cruise Expert] always works hard to secure the bookings we have chosen and guides us through the process. She is always available to help and her advise is spot on.
James C.
We are residents in another country, and have used [our Cruise Expert] for years as we try to cruise around the entire world. She offers great service and stellar communication.
Dave O.
[Our Cruise Expert]does a wonderful job for me. I have had no glitches and I can count on things running smoothly when [our Cruise Expert] makes my arrangements.
Barbara H.
Overview
A South American river cruise offers an incredible way to explore the continent’s diverse landscapes, rich cultures, and unique ecosystems.
The Amazon River, one of the most iconic waterways, takes travelers deep into the heart of the rainforest, where they can encounter exotic wildlife, indigenous communities, and lush, untouched nature.
Other rivers, such as the Parana and the Magdalena, provide access to vibrant cities, colonial towns, and stunning waterfalls, offering a blend of adventure and cultural immersion. Whether spotting pink dolphins in the Amazon or cruising past the dramatic landscapes of the Andes, each journey reveals a new and fascinating side of South America.
Beyond its natural wonders, a river cruise in South America gives an up-close look at local traditions, music, and cuisine. Passengers can visit bustling riverfront markets, sample regional specialties, and witness traditional crafts being made by local artisans.
Whether seeking adventure, wildlife encounters, or cultural discoveries, a South America river cruise provides a unique and unforgettable way to explore this diverse and breathtaking continent.
Actively seek out diverse Amazonian fauna with your guides. Spot various species of monkeys, elusive sloths, iconic pink river dolphins, colorful macaws and toucans, caiman, and a vast array of other birds and insects in their natural rainforest habitat.
Navigate narrow tributaries and hidden lagoons in motorized skiffs for intimate wildlife viewing opportunities. Embark on guided walks into the rainforest with expert naturalist guides to discover the intricate ecosystem, medicinal plants, and smaller creatures often missed from the water.
Visit remote riverside villages to gain insight into the daily lives, traditions, and culture of indigenous communities. Learn about their ancestral knowledge of the rainforest, local crafts, and the challenges and realities of life along the river.
Benefit immensely from the deep knowledge of onboard naturalist guides. They lead all excursions, deliver informative lectures on local ecology and wildlife, and are skilled at spotting and identifying the diverse flora and fauna you'll encounter.
Many cruises offer memorable experiences like piranha fishing (and perhaps tasting your catch!), night skiff safaris to search for nocturnal creatures such as caiman using spotlights, or kayaking/canoeing in tranquil blackwater creeks and lakes.
