Holland America Cruises from San Antonio, Santiago, Chile

Plaza de Armas square in Santiago, Chile.

Upcoming Holland America Cruises from San Antonio, Santiago, Chile

8 Results

Taxes and fees included in all prices shown

Sort

A panoramic view of the rugged, green landscape of the Falkland Islands, with a low cloud covering the top of a hill and the blue sea in the foreground under a dramatic sky.

Exclusive Onboard Savings, Events & Reduced Fares with Mariner Society*

14-night South American Passage Cruise

Santiago (San Antonio)

Puerto Chacabuco

Canal Sarmiento

Aboard

Oosterdam

From

San Antonio, Santiago, Chile

1 Sailing

Dec 4, 2025

1 Sailing

Dec 4, 2025

Published prices from

$3,009

per person*

taxes & fees included

A breathtaking action shot of a killer whale breaching from the deep blue Antarctic waters, with a massive glacier and icebergs in the background.

Exclusive Onboard Savings, Events & Reduced Fares with Mariner Society*

22-night South America & Antarctica Cruise

Santiago (San Antonio)

Puerto Chacabuco

Aboard

Oosterdam

From

San Antonio, Santiago, Chile

3 Sailings

Jan 9, 2026 - Jan 8, 2028

3 Sailings

Jan 9, 2026 - Jan 8, 2028

Published prices from

$5,979

per person*

taxes & fees included

A panoramic landscape view of the lush, green volcanic mountains and hills of Moorea, French Polynesia, with the Opunohu and Cook's Bays on either side.

Exclusive Onboard Savings, Events & Reduced Fares with Mariner Society*

41-night Grand World Voyage Cruise

Santiago (San Antonio)

Pitcairn Island

Aboard

Volendam

From

San Antonio, Santiago, Chile

1 Sailing

Feb 10, 2026

1 Sailing

Feb 10, 2026

Published prices from

$7,694

per person*

taxes & fees included

A beautiful landscape of the Cockburn Channel, featuring a rainbow arching over a snow-capped mountain slope, while a grassy hillside descends to the calm turquoise water.

Exclusive Onboard Savings, Events & Reduced Fares with Mariner Society*

14-night South America Passage Cruise

Santiago (San Antonio)

Puerto Chacabuco

Canal Sarmiento

Aboard

Oosterdam

From

San Antonio, Santiago, Chile

1 Sailing

Feb 22, 2026

1 Sailing

Feb 22, 2026

Published prices from

$3,149

per person*

taxes & fees included

Panama City skyline from water.

Exclusive Onboard Savings, Events & Reduced Fares with Mariner Society*

17-night Inca & Panama Canal Discovery Cruise

Santiago (San Antonio)

General San Martin

Trujillo (Salaverry)

Aboard

Oosterdam

From

San Antonio, Santiago, Chile

1 Sailing

Mar 22, 2026

1 Sailing

Mar 22, 2026

Published prices from

$3,049

per person*

taxes & fees included

Plaza de Armas square in Santiago, Chile.

Exclusive Onboard Savings, Events & Reduced Fares with Mariner Society*

15-night South America Pathways: Chilean Fjords & Glaciers Cruise

Santiago (San Antonio)

Puerto Chacabuco

Aboard

Oosterdam

From

San Antonio, Santiago, Chile

2 Sailings

Dec 4, 2026 - Dec 2, 2027

2 Sailings

Dec 4, 2026 - Dec 2, 2027

Published prices from

$3,339

per person*

taxes & fees included

A massive, stunning blue and white glacier in the Sarmiento Channel, Patagonia, Chile, with its dramatic crevasses and ice formations towering over the deep blue water.

Exclusive Onboard Savings, Events & Reduced Fares with Mariner Society*

14-night South America Pathways: Chilean Fjords & Glaciers Cruise

Santiago (San Antonio)

Puerto Chacabuco

Aboard

Oosterdam

From

San Antonio, Santiago, Chile

2 Sailings

Feb 23, 2027 - Feb 21, 2028

2 Sailings

Feb 23, 2027 - Feb 21, 2028

Published prices from

$3,174

per person*

taxes & fees included

A blue, rustic fishing boat floats in the turquoise and clear water of a tropical beach near Trujillo, Peru, with a small, green island in the distance.

Exclusive Onboard Savings, Events & Reduced Fares with Mariner Society*

16-night Inca & Panama Canal Discovery: Lima Overnight Cruise

Santiago (San Antonio)

General San Martin

Trujillo (Salaverry)

Aboard

Oosterdam

From

San Antonio, Santiago, Chile

2 Sailings

Mar 24, 2027 - Mar 21, 2028

2 Sailings

Mar 24, 2027 - Mar 21, 2028

Published prices from

$3,764

per person*

taxes & fees included

*Rates and offers are per person, in US Dollars, based on double occupancy, capacity controlled, subject to availability and confirmation, and may change without notice. Government taxes and fees are included. Rates and offers are available for select dates and categories only. Additional restrictions may apply. Call 1-800-377-9383 for full terms and conditions.