22-night South America & Antarctica Cruise From San Antonio, Santiago, Chile

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Casa Rosada government building in Buenos Aires.
Holland America's Nieuw Amsterdam at sea.
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Sailing Jan 8, 2028

from $5,279 per person* taxes and fees included

Your 22-night South America Cruise at a Glance

Sailings aboard Nieuw Amsterdam depart from San Antonio, Santiago, Chile with 18 stops in ports-of-call including Puerto Montt, Port Stanley, and Puerto Chacabuco. The Cruise Web can help you find the best deals and stateroom prices on the next sailing January 8, 2028.

Santiago is a dynamic capital city nestled between the Andes and the Pacific, where urban energy meets natural beauty. Before you depart San Antonio, Santiago, Chile, we can help you plan travel and accommodations for your South America cruise.

Destination

South America

Stops on your South America voyage will include Chilean Fjords on day 5 and Amalia Glacier on day 6. We can help you with excursions and making the most of any itinerary.

Cruise Ship

Nieuw Amsterdam

Nieuw Amsterdam, built in 2010 and refurbished in 2019, carries 2,106 passengers with a crew of 929. Ask us about dining options like Nami Sushi and entertainment like Billboard Onboard!

Amazing food and superb service make Holland America one of the longest running cruise lines. We can help you maximize deals on South America cruises aboard Nieuw Amsterdam or 10 of Holland America’s other ships.