South America Cruise Deals

Christ the Redeemer statue stands tall over Rio de Janeiro, Brazil, with arms outstretched against a clear blue sky.

Upcoming South America Cruise Deals

Filter

811 Results

Sort

Barranquilla city skyline at sunset.
Up to $2,500 Off + $250 Onboard Credit + Reduced Airfare*
AmaWaterways' Logo.

7-night Wonders Of Colombia Cruise From Cartagena, Colombia

Aboard

AmaMelodia

From

Cartagena, Colombia

Published prices from

$3,299

per person*

taxes & fees included

A beautiful colonial-era church in Mompox, Colombia, with its vibrant yellow facade, ornate bell tower, and bright red dome standing out against a clear blue sky.
Up to $500 FREE Onboard Credit*+ 3 more offers
TCW EXCLUSIVE
AmaWaterways' Logo.

7-night Wonders Of Colombia with 3-nights in Panama City Post-Cruise Cruise/Land Package From Cartagena, Colombia

Aboard

AmaMelodia

From

Cartagena, Colombia

Plaza Mayor in Lima, Peru.
75% off 2nd Guest + FREE 3rd/4th/5th Guests + up to $850 Instant Savings*
Celebrity Cruise Line logo

16-night Galapagos Inner Loop & Machu Picchu Cruise/Land Package From Quito, Ecuador

Aboard

Celebrity Flora

From

Quito, Ecuador

Galapagos land iguana on rocks.
75% off 2nd Guest + FREE 3rd/4th/5th Guests + up to $850 Instant Savings*
Celebrity Cruise Line logo

11-night Quito & Galapagos Inner Loop Cruise/Land Package From Quito, Ecuador

Aboard

Celebrity Flora

From

Quito, Ecuador

Galapagos land iguana on rocks.
75% off 2nd Guest + FREE 3rd/4th/5th Guests + up to $850 Instant Savings*
Celebrity Cruise Line logo

10-night Quito & Galapagos Inner Loop Cruise/Land Package From Quito, Ecuador

Aboard

Celebrity Flora

From

Quito, Ecuador

A sunny view of the colorful waterfront of Willemstad, Curacao, with its iconic pastel-colored Dutch colonial buildings lining the Handelskade street and a ship docked in the port.
Up to $500 FREE Onboard Credit*+ 3 more offers
TCW EXCLUSIVE
Royal Caribbean logo

7-night Southern Caribbean Cruise From Colon, Panama

Aboard

Grandeur of the Seas

From

Colon, Panama

Published prices from

$993

per person*

taxes & fees included

Modern Panama City skyline with skyscrapers.
Up to $2,500 Off + $250 Onboard Credit + Reduced Airfare*
AmaWaterways' Logo.

7-night Magic Of Colombia With 3-nights Medellín Pre Cruise and 3 nights in Panama City Post-Cruise Cruise/Land Package From Medellín, Colombia

Aboard

AmaMelodia

From

Medellín, Colombia

Published prices from

$7,016

per person*

taxes & fees included

Aerial view of Medellín River and city with mountains in Colombia.
Up to $2,500 Off + $250 Onboard Credit + Reduced Airfare*
AmaWaterways' Logo.

7-night Magic Of Colombia With 3-nights Medellín Pre Cruise Cruise/Land Package From Medellín, Colombia

Aboard

AmaMelodia

From

Medellín, Colombia

Published prices from

$4,841

per person*

taxes & fees included

A close-up of a Galapagos land iguana with its scaly skin and spiky crest, blending into the dry grass on Isla Bartolomé.
75% off 2nd Guest + FREE 3rd/4th/5th Guests + up to $850 Instant Savings*
Celebrity Cruise Line logo

7-night Galapagos Inner Loop Cruise From Isla Baltra, Galapagos Islands

Aboard

Celebrity Flora

From

Isla Baltra, Galapagos Islands

Published prices from

$9,735

per person*

taxes & fees included

A sunny view of the colorful waterfront of Willemstad, Curacao, with its iconic pastel-colored Dutch colonial buildings lining the Handelskade street and a ship docked in the port.
Up to $500 FREE Onboard Credit*+ 3 more offers
TCW EXCLUSIVE
Royal Caribbean logo

7-night Southern Caribbean Cruise From Cartagena, Colombia

Aboard

Grandeur of the Seas

From

Cartagena, Colombia

Published prices from

$1,114

per person*

taxes & fees included

Modern Panama City skyline with skyscrapers.
Up to $500 FREE Onboard Credit*+ 1 more offer
TCW EXCLUSIVE
AmaWaterways' Logo.

7-Night Magic of Colombia With 3 Nights In Medellín Pre Cruise And 3 Nights In Panama City Post Cruise Cruise/Land Package From Medellín, Colombia

Aboard

AmaMagdalena

From

Medellín, Colombia

Published prices from

$6,866

per person*

taxes & fees included

Colorful colonial balconies in Cartagena.
Up to $500 FREE Onboard Credit*+ 1 more offer
TCW EXCLUSIVE
AmaWaterways' Logo.

7-night Magic Of Colombia With 3-nights Medellín Pre Cruise Cruise/Land Package From Medellín, Colombia

Aboard

AmaMagdalena

From

Medellín, Colombia

Published prices from

$4,691

per person*

taxes & fees included

An aerial view of the verdant, rolling hills and a peninsula jutting out into the deep blue waters of Vanimo, a picturesque coastal town in Papua New Guinea.
Up to $500 FREE Onboard Credit*+ 2 more offers
TCW EXCLUSIVE
Silversea logo

77-night Grand South Pacific Expedition From Perth (Fremantle), Australia

Aboard

Silver Cloud

From

Perth (Fremantle), Australia

A beautiful colonial-era church in Mompox, Colombia, with its vibrant yellow facade, ornate bell tower, and bright red dome standing out against a clear blue sky.
Up to $2,500 Off + $250 Onboard Credit + Reduced Airfare*
AmaWaterways' Logo.

7-night Wonders of Colombia with 3 Nights in Medellin and 2 Nights in Cartagena Pre-Cruise Cruise/Land Package From Medellín, Colombia

Aboard

AmaMelodia

From

Medellín, Colombia

Published prices from

$6,099

per person*

taxes & fees included

A beautiful colonial-era church in Mompox, Colombia, with its vibrant yellow facade, ornate bell tower, and bright red dome standing out against a clear blue sky.
Up to $2,500 Off + $250 Onboard Credit + Reduced Airfare*
AmaWaterways' Logo.

7-night Wonders Of Colombia With 3-nights In Medellín, 2-nights In Cartagena Pre Cruise And 3-nights In Panama City Post Cruise Cruise/Land Package From Medellín, Colombia

Aboard

AmaMelodia

From

Medellín, Colombia

Published prices from

$8,024

per person*

taxes & fees included

A riverboat with a red roof and seating for passengers travels along the calm Magdalena River, with lush green trees lining the banks of Sitio Nuevo, Colombia.
Up to $2,500 Off + $250 Onboard Credit + Reduced Airfare*
AmaWaterways' Logo.

7-night Magic Of Colombia With 3-nights Panama Post Cruise Cruise/Land Package From Barranquilla, Colombia

Aboard

AmaMagdalena

From

Barranquilla, Colombia

Colorful colonial balconies in Cartagena.
Up to $2,500 Off + $250 Onboard Credit + Reduced Airfare*
AmaWaterways' Logo.

7-night Magic of Colombia Cruise From Barranquilla, Colombia

Aboard

AmaMagdalena

From

Barranquilla, Colombia

Published prices from

$2,999

per person*

taxes & fees included

A colorful residential area of Ciudad Bolivar, Bogotá, with bright yellow, blue, and pink houses built on a hillside, with a cable car visible in the sky.
Up to $500 FREE Onboard Credit*+ 2 more offers
TCW EXCLUSIVE
Silversea logo

7-night Galapagos Island Cruise From Isla San Cristobal, Galapagos Islands

Aboard

Silver Origin

From

Isla San Cristobal, Galapagos Islands

Modern Panama City skyline with skyscrapers.
Up to $2,500 Off + $250 Onboard Credit + Reduced Airfare*
AmaWaterways' Logo.

7-night Wonders Of Colombia With 3-nights In Medellín, 2-nights In Cartagena Pre Cruise And 3-nights In Panama City Post Cruise Cruise/Land Package From Medellín, Colombia

Aboard

AmaMagdalena

From

Medellín, Colombia

Published prices from

$7,874

per person*

taxes & fees included

Aerial view of Medellín River and city with mountains in Colombia.
Up to $2,500 Off + $250 Onboard Credit + Reduced Airfare*
AmaWaterways' Logo.

7-night Wonders Of Colombia With 3-nights In Medellín, 2-nights In Cartagena Pre Cruise Cruise/Land Package From Medellín, Colombia

Aboard

AmaMagdalena

From

Medellín, Colombia

Published prices from

$5,699

per person*

taxes & fees included

Aerial view of Magangué, Colombia, a densely built town with colorful roofs, bordered by a murky river/lake and lush green land, under an overcast sky.
Up to $500 FREE Onboard Credit*+ 3 more offers
TCW EXCLUSIVE
AmaWaterways' Logo.

7-night Wonders Of Colombia With 2-nights In Cartagena Pre Cruise Cruise/Land Package From Cartagena, Colombia

Aboard

AmaMelodia

From

Cartagena, Colombia

Published prices from

$4,289

per person*

taxes & fees included

A beautiful colonial-era church in Mompox, Colombia, with its vibrant yellow facade, ornate bell tower, and bright red dome standing out against a clear blue sky.
Up to $2,500 Off + $250 Onboard Credit + Reduced Airfare*
AmaWaterways' Logo.

7-night Wonders Of Colombia With 2-nights In Cartagena Pre Cruise Cruise/Land Package From Cartagena, Colombia

Aboard

AmaMagdalena

From

Cartagena, Colombia

Published prices from

$4,139

per person*

taxes & fees included

A beautiful colonial-era church in Mompox, Colombia, with its vibrant yellow facade, ornate bell tower, and bright red dome standing out against a clear blue sky.
Up to $2,500 Off + $250 Onboard Credit + Reduced Airfare*
AmaWaterways' Logo.

7-night Wonders Of Colombia with 3-nights in Panama City Post-Cruise Cruise/Land Package From Cartagena, Colombia

Aboard

AmaMagdalena

From

Cartagena, Colombia

A breathtaking view of the world's tallest waterfall, Angel Falls, cascading down a towering Auyán-tepui cliff face in Venezuela's lush Canaima National Park, surrounded by dense jungle.
Up to $2,500 Off + $250 Onboard Credit + Reduced Airfare*
AmaWaterways' Logo.

7-night Wonders Of Colombia Cruise From Cartagena, Colombia

Aboard

AmaMagdalena

From

Cartagena, Colombia

Published prices from

$3,149

per person*

taxes & fees included

Kicker Rock in the Galapagos Islands, a large volcanic rock formation with two peaks rising from the calm ocean, lit by the warm glow of the setting sun.
Up to $500 FREE Onboard Credit*+ 1 more offer
TCW EXCLUSIVE
Silversea logo

14-night Galapagos Islands Cruise From Isla San Cristobal, Galapagos Islands

Aboard

Silver Origin

From

Isla San Cristobal, Galapagos Islands

*Rates and offers are per person, in US Dollars, based on double occupancy, capacity controlled, subject to availability and confirmation, and may change without notice. Government taxes and fees are included. Rates and offers are available for select dates and categories only. Additional restrictions may apply. Call 1-800-377-9383 for full terms and conditions.

More to Explore

Cruise Lines

Oceania Cruises

Holland America Line

Azamara

Explora Journeys

Viking Expedition Cruises

Destinations

South American River

Danube River

Ganges River

Po River

Mexico

Ports

Monopoli, Italy

Garibaldi Glacier, Chile

Iguassu Falls (Brazilian Side), Brazil

Bay of Biscay

Brahmaputra River, Bangladesh

Cruise Ships

Viking Ingvi

Aria Amazon

AmaSiena

Avalon Imagery II

Azamara Pursuit