South America Cruise Deals

Christ the Redeemer statue stands tall over Rio de Janeiro, Brazil, with arms outstretched against a clear blue sky.

816 Results

Sort

An aerial view of a vibrant yellow colonial church with a red-tiled roof and bell tower, the main landmark of the historic town of Santa Bárbara de Pinto in Colombia.
FREE Excursions, Specialty Dining, Wi-Fi & More*+ 1 more offer
AmaWaterways

7-night Magic of Colombia Cruise

Aboard

AmaMagdalena

From

Barranquilla, Colombia

Published prices from

$3,049

per person*

taxes & fees included

A large marine iguana sunbathing on a black volcanic rock at Cerro Brujo beach, with a powerful wave crashing in the turquoise waters of the Galapagos Islands.
FREE Butler Service, Gourmet Dining & More*
Silversea logo

7-night Galapagos Islands Cruise

Aboard

Silver Origin

From

Isla San Cristobal, Galapagos Islands

Published prices from

$12,200

per person*

taxes & fees included

A vibrant beach scene in Búzios, Brazil, with people swimming and relaxing under white umbrellas on the sand, next to lush green hills and a small white building.
Military Families Save 10%*+ 1 more offer
MSC Cruises logo

6 nights Northeast Brazil

Aboard

MSC Seaview

From

Santos (São Paulo), Brazil

Published prices from

$839

per person*

taxes & fees included

Oranjestad, Aruba harbor with boats and colorful Dutch architecture.
FREE All-Inclusive Upgrade + FREE Hotel Stay + up to $2,000 Onboard Credit*+ 1 more offer
Windstar

7-night Enchanting Colombia And Panamanian Islands Cruise

Aboard

Wind Spirit

From

Colon, Panama

Published prices from

$3,115

per person*

taxes & fees included

Galapagos land iguana on rocks.
75% off 2nd Guest + 3rd, 4th, & 5th Guests Sail FREE + Bonus Savings*+ 2 more offers
Celebrity Cruise Line logo

7-night Galapagos Outer Loop Cruise

Aboard

Celebrity Flora

From

Isla Baltra, Galapagos Islands

Published prices from

$7,363

per person*

taxes & fees included

Colorful colonial balconies in Cartagena.
FREE Dining, Onboard Activities & More*+ 1 more offer
Royal Caribbean logo

7-night Southern Caribbean Cruise

Aboard

Serenade of the Seas

From

Cartagena, Colombia

Published prices from

$1,455

per person*

taxes & fees included

A scenic panoramic view of Ilhabela, Brazil, showing a long, sandy beach with turquoise water, a river flowing to the sea, and lush, green mountains under a bright blue sky.
Military Families Save 10%*+ 1 more offer
MSC Cruises logo

3 nights Tropical Brazil

Aboard

MSC Armonia

From

Rio de Janeiro, Brazil

Published prices from

$763

per person*

taxes & fees included

An aerial view of a vibrant yellow colonial church with a red-tiled roof and bell tower, the main landmark of the historic town of Santa Bárbara de Pinto in Colombia.
FREE Excursions, Specialty Dining, Wi-Fi & More*+ 1 more offer
AmaWaterways

7-night Wonders of Colombia with 2 Nights in Cartagena Pre-Cruise Cruise/Land Package

Aboard

AmaMelodia

From

Cartagena, Colombia

Published prices from

$5,139

per person*

taxes & fees included

Barranquilla city skyline at sunset.
FREE Excursions, Specialty Dining, Wi-Fi & More*+ 1 more offer
AmaWaterways

7-night Wonders of Colombia with 3 Nights in Medellin, 2 Nights in Cartagena Pre-Cruise and 3 Nights in Panama City Post-Cruise Cruise/Land Package

Aboard

AmaMagdalena

From

Medellín, Colombia

A close-up of a row of colonial buildings with vibrant, colorful facades in San Basilio de Palenque, Colombia, featuring brightly painted balconies and red-tiled rooftops.
FREE Excursions, Specialty Dining, Wi-Fi & More*+ 1 more offer
AmaWaterways

7-night Wonders of Colombia with 3 Nights in Medellin, 2 Nights in Cartagena Pre-Cruise Cruise/Land Package

Aboard

AmaMagdalena

From

Medellín, Colombia

A scenic aerial shot of the tropical Morro de Sao Paulo beach in Brazil, showing the turquoise Atlantic Ocean, a long stretch of golden sand, and a village with red-roofed houses nestled against a lush green hill.
Military Families Save 10%*+ 1 more offer
MSC Cruises logo

7 nights Tropical Brazil

Aboard

MSC Sinfonia

From

Santos (São Paulo), Brazil

Published prices from

$808

per person*

taxes & fees included

An aerial shot of the port city of Ushuaia, Argentina, at dusk, showing city lights along the Beagle Channel with the snow-capped Andes Mountains in the background.
FREE Butler Service, Gourmet Dining & More*
Silversea logo

30-night South America Cruise

Aboard

Silver Whisper

From

Rio de Janeiro, Brazil

Casa Rosada government building in Buenos Aires.
FREE Wi-Fi, Dining, Spa Access & More*+ 1 more offer
Viking

17-night South America & The Chilean Fjords Cruise

Aboard

Viking Jupiter

From

Valparaiso (Santiago), Chile

Published prices from

$7,099

per person*

taxes & fees included

A dramatic sunset over Lake Arenal in Costa Rica, with a majestic, conical Arenal Volcano emitting a plume of smoke and fiery clouds into the orange sky.
FREE All-Inclusive Upgrade + FREE Hotel Stay + up to $2,000 Onboard Credit*+ 1 more offer
Windstar

11-night Monteverde Cloud Forest & Arenal Volcano Cruise/Land Package

Aboard

Star Pride

From

San Jose, Costa Rica

Casa Rosada government building in Buenos Aires.
Save up to 30% on Last Minute Sailings*+ 1 more offer
Seabourn logo

21-night Antarctica, South Georgia & Falkland Holiday Cruise

Aboard

Seabourn Pursuit

From

Buenos Aires, Argentina

Rio de Janeiro panoramic with Sugarloaf Mountain and Guanabara Bay.
FREE Butler Service, Gourmet Dining & More*
Silversea logo

12-night South America Cruise

Aboard

Silver Whisper

From

Rio de Janeiro, Brazil

Published prices from

$7,800

per person*

taxes & fees included

A vibrant beach scene in Búzios, Brazil, with people swimming and relaxing under white umbrellas on the sand, next to lush green hills and a small white building.
Up to 30% off + $250 Onboard Credit + Kids Sail FREE*
MSC Cruises logo

6 nights Northeast Brazil

Aboard

MSC Seaview

From

Salvador de Bahia, Brazil

Published prices from

$905

per person*

taxes & fees included

A vibrant beach scene in Búzios, Brazil, with people swimming and relaxing under white umbrellas on the sand, next to lush green hills and a small white building.
Military Families Save 10%*+ 1 more offer
MSC Cruises logo

3 nights Tropical Brazil

Aboard

MSC Preziosa

From

Santos (São Paulo), Brazil

Published prices from

$442

per person*

taxes & fees included

Aerial view of Magangué, Colombia, a densely built town with colorful roofs, bordered by a murky river/lake and lush green land, under an overcast sky.
FREE Excursions, Specialty Dining, Wi-Fi & More*+ 1 more offer
AmaWaterways

7-night Wonders of Colombia Cruise

Aboard

AmaMelodia

From

Cartagena, Colombia

Published prices from

$4,239

per person*

taxes & fees included

Aerial view of Magangué, Colombia, a densely built town with colorful roofs, bordered by a murky river/lake and lush green land, under an overcast sky.
FREE Excursions, Specialty Dining, Wi-Fi & More*+ 1 more offer
AmaWaterways

7-night Wonders of Colombia with 3 Nights in Panama City Post-Cruise Cruise/Land Package

Aboard

AmaMelodia

From

Cartagena, Colombia

An aerial shot of the port city of Ushuaia, Argentina, at dusk, showing city lights along the Beagle Channel with the snow-capped Andes Mountains in the background.
FREE Excursions, Specialized Gear, Dining & More*+ 1 more offer
Viking

12-night Antarctic Explorer Cruise

Aboard

Viking Polaris

From

Buenos Aires, Argentina

Published prices from

$14,995

per person*

taxes & fees included

A panoramic view of the rugged, green landscape of the Falkland Islands, with a low cloud covering the top of a hill and the blue sea in the foreground under a dramatic sky.
Princess Plus - Drinks, Wi-Fi, Tips Included & More*+ 1 more offer
Princess Cruises logo

22-night Iguazu Falls Adventure Cruisetour #1F

Aboard

Sapphire Princess

From

Rio de Janeiro, Brazil

Published prices from

$8,287

per person*

taxes & fees included

An aerial view of the Balneário Camboriú Ferris wheel, a landmark attraction on the Brazilian coastline, with the city's impressive skyline and sandy beach in the background.
Military Families Save 10%*+ 1 more offer
MSC Cruises logo

8 nights Brazil Ex Argentina

Aboard

MSC Fantasia

From

Montevideo, Uruguay

Published prices from

$1,799

per person*

taxes & fees included

A scenic view of a majestic waterfall cascading down a sheer cliff face into a lush green forest in the Rio Grande region of Brazil.
Give $250, Get $250*+ 1 more offer
Regent Seven Seas

11-night South American Splendor Cruise

Aboard

Seven Seas Splendor

From

Rio de Janeiro, Brazil

Published prices from

$12,899

per person*

taxes & fees included

Casa Rosada government building in Buenos Aires.
Save up to 30% on Last Minute Sailings*+ 1 more offer
Seabourn logo

11-night The Great White Continent Cruise

Aboard

Seabourn Venture

From

Buenos Aires, Argentina

Published prices from

$11,473

per person*

taxes & fees included


*Rates and offers are per person, in US Dollars, based on double occupancy, capacity controlled, subject to availability and confirmation, and may change without notice. Government taxes and fees are included. Rates and offers are available for select dates and categories only. Additional restrictions may apply. Call 1-800-377-9383 for full terms and conditions.