South America Cruise Deals

Christ the Redeemer statue stands tall over Rio de Janeiro, Brazil, with arms outstretched against a clear blue sky.

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A beautiful colonial-era church in Mompox, Colombia, with its vibrant yellow facade, ornate bell tower, and bright red dome standing out against a clear blue sky.
FREE Experiences, Specialty Dining, Wi-Fi & More*
AmaWaterways' Logo.

7-night Wonders Of Colombia With 3-nights In Medellín, 2-nights In Cartagena Pre Cruise And 3-nights In Panama City Post Cruise Cruise/Land Package

Aboard

AmaMelodia

From

Medellín, Colombia

Published prices from

$7,874

per person*

taxes & fees included

A close-up shot of a magnificent land iguana, native to the Galapagos Islands, resting on a rocky shore with its spiky crest and scaly skin visible.
Active & Retired Military Members Save up to $200*+ 1 more offer
Celebrity Cruise Line logo

16-night Galapagos Outer Loop & Machu Picchu Cruise/Land Package

Aboard

Celebrity Flora

From

Quito, Ecuador

A close-up shot of a marine iguana, a unique species from the Galápagos Islands, basking in the sun among a group of other iguanas on the lava rocks of Punta Espinoza.
Active & Retired Military Members Save up to $200*+ 1 more offer
Celebrity Cruise Line logo

11-night Quito & Galapagos Outer Loop Cruise/Land Package

Aboard

Celebrity Flora

From

Quito, Ecuador

A group of marine iguanas, a native species of the Galápagos Islands, sunning themselves on a rocky lava shoreline with the deep blue ocean and white waves in the background at Punta Moreno.
Active & Retired Military Members Save up to $200*+ 1 more offer
Celebrity Cruise Line logo

10-night Quito & Galapagos Outer Loop Cruise/Land Package

Aboard

Celebrity Flora

From

Quito, Ecuador

An aerial view of the historic walled city of Cartagena, Colombia, showing the vibrant architecture of churches and colonial buildings, with the ocean in the background under a soft morning light.
FREE Experiences, Specialty Dining, Wi-Fi & More*
AmaWaterways' Logo.

7-night Wonders of Colombia with 3 Nights in Medellin and 2 Nights in Cartagena Pre-Cruise Cruise/Land Package

Aboard

AmaMelodia

From

Medellín, Colombia

Published prices from

$5,699

per person*

taxes & fees included

A riverboat with a red roof and seating for passengers travels along the calm Magdalena River, with lush green trees lining the banks of Sitio Nuevo, Colombia.
FREE Experiences, Specialty Dining, Wi-Fi & More*
AmaWaterways' Logo.

7-night Magic of Colombia Cruise

Aboard

AmaMagdalena

From

Barranquilla, Colombia

Published prices from

$3,149

per person*

taxes & fees included

Aerial view of Magangué, Colombia, a densely built town with colorful roofs, bordered by a murky river/lake and lush green land, under an overcast sky.
FREE Experiences, Specialty Dining, Wi-Fi & More*
AmaWaterways' Logo.

7-night Magic Of Colombia With 3-nights Panama Post Cruise Cruise/Land Package

Aboard

AmaMagdalena

From

Barranquilla, Colombia

A beautiful panoramic view of the Ilha Grande coastline in Brazil, showcasing the vibrant turquoise sea, lush green tropical islands, and misty mountains on the horizon.
Exclusive Savings & Events with Oceania Club*
Oceania Cruises

10-night Brazilian Rhythms - 2026 World Voyage Segment

Aboard

Vista

From

Rio de Janeiro, Brazil

Published prices from

$4,449

per person*

taxes & fees included

Immaculate Conception Cathedral in Colon.
Up to $500 FREE Onboard Credit*+ 2 more offers
TCW EXCLUSIVE
Royal Caribbean logo

7-night Southern Caribbean Cruise

Aboard

Serenade of the Seas

From

Colon, Panama

Published prices from

$1,364

per person*

taxes & fees included

Miami skyline at dusk, showcasing vibrant colors and reflections shimmering in the water below.
Up to $500 FREE Onboard Credit*+ 2 more offers
TCW EXCLUSIVE
Holland America logo

22-night Eastern Caribbean & Panama Canal Cruise

Aboard

Zuiderdam

From

Miami, Florida

A large marine iguana sunbathing on a black volcanic rock at Cerro Brujo beach, with a powerful wave crashing in the turquoise waters of the Galapagos Islands.
FREE Butler Service, Gourmet Dining & More*+ 1 more offer
Silversea logo

7-night Galapagos Islands Cruise

Aboard

Silver Origin

From

Isla San Cristobal, Galapagos Islands

Published prices from

$12,400

per person*

taxes & fees included

Rio de Janeiro panoramic with Sugarloaf Mountain and Guanabara Bay.
Military Families Save 10%*
MSC Cruises logo

7 nights Northeast Brazil

Aboard

MSC Armonia

From

Rio de Janeiro, Brazil

Published prices from

$942

per person*

taxes & fees included

A scenic aerial shot of the tropical Morro de Sao Paulo beach in Brazil, showing the turquoise Atlantic Ocean, a long stretch of golden sand, and a village with red-roofed houses nestled against a lush green hill.
Military Families Save 10%*
MSC Cruises logo

7 nights Northeast Brazil

Aboard

MSC Seaview

From

Santos (São Paulo), Brazil

Published prices from

$668

per person*

taxes & fees included

Two young elephant seals playing in a small pool of water on a beach covered in seaweed, with icebergs and a dramatic cloudy sky in the background of Drake Passage.
FREE Butler Service, Gourmet Dining & More*+ 1 more offer
Silversea logo

12-night Antarctica Cruise

Aboard

Silver Endeavour

From

Puerto Williams, Chile

Published prices from

$22,700

per person*

taxes & fees included

A close-up of a fluffy, young emperor penguin chick with its beak open, showcasing the unique wildlife of the Antarctic Peninsula.
Princess Plus - Drinks, Wi-Fi, Tips Included & More*+ 2 more offers
Princess Cruises logo

17-night Antarctica Cruise

Aboard

Sapphire Princess

From

Buenos Aires, Argentina

Casa Rosada government building in Buenos Aires.
Princess Plus - Drinks, Wi-Fi, Tips Included & More*+ 2 more offers
Princess Cruises logo

35-night Antarctica & South American Grand Adventure Cruise

Aboard

Sapphire Princess

From

Buenos Aires, Argentina

A beautiful image of a narrow, stone-paved street in a medieval Italian village near Livorno, adorned with ivy-covered walls, potted plants, and colorful flowers, giving a feeling of tranquility.
Princess Plus - Drinks, Wi-Fi, Tips Included & More*+ 2 more offers
Princess Cruises logo

42-night Ultimate Antarctica & Mediterranean Adventure Cruise

Aboard

Sapphire Princess

From

Buenos Aires, Argentina

An aerial shot of the port city of Ushuaia, Argentina, at dusk, showing city lights along the Beagle Channel with the snow-capped Andes Mountains in the background.
Save up to 30% on Last Minute Sailings*+ 1 more offer
Seabourn logo

13-night Antarctica Exploration Cruise

Aboard

Seabourn Pursuit

From

Buenos Aires, Argentina

Published prices from

$14,448

per person*

taxes & fees included

Galapagos land iguana on rocks.
Active & Retired Military Members Save up to $200*+ 1 more offer
Celebrity Cruise Line logo

7-night Galapagos Outer Loop Cruise

Aboard

Celebrity Flora

From

Isla Baltra, Galapagos Islands

Published prices from

$8,529

per person*

taxes & fees included

A scenic aerial shot of the tropical Morro de Sao Paulo beach in Brazil, showing the turquoise Atlantic Ocean, a long stretch of golden sand, and a village with red-roofed houses nestled against a lush green hill.
Military Families Save 10%*
MSC Cruises logo

7 nights Southeast South America

Aboard

MSC Preziosa

From

Santos (São Paulo), Brazil

Published prices from

$880

per person*

taxes & fees included

Colorful colonial balconies in Cartagena.
FREE Dining, Onboard Activities & More*+ 1 more offer
Royal Caribbean logo

7-night Southern Caribbean Cruise

Aboard

Serenade of the Seas

From

Cartagena, Colombia

Published prices from

$1,567

per person*

taxes & fees included

Rocky beach and palm trees in Barbados.
FREE All-Inclusive Upgrade + FREE Hotel Stay + up to $2,300 Onboard Credit*+ 1 more offer
Windstar

15-night Star Collector: Windward Islands & Spanish New World Cruise

Aboard

Wind Surf

From

Bridgetown, Barbados

Published prices from

$7,766

per person*

taxes & fees included

An aerial view of the Kralendijk waterfront in Bonaire, showcasing the contrast between the deep blue ocean and the shallow turquoise water near the shore, with sailboats anchored offshore.
FREE Butler Service, Gourmet Dining & More*+ 1 more offer
Silversea logo

9-night Southern Caribbean Cruise

Aboard

Silver Shadow

From

Bridgetown, Barbados

A panoramic shot of a wide, calm river flowing through a lush, green landscape under a bright blue sky with white clouds in Nueva Venecia, Colombia.
FREE Experiences, Specialty Dining, Wi-Fi & More*
AmaWaterways' Logo.

7-night Wonders Of Colombia With 2-nights In Cartagena Pre Cruise Cruise/Land Package

Aboard

AmaMelodia

From

Cartagena, Colombia

Published prices from

$4,139

per person*

taxes & fees included

A beautiful colonial-era church in Mompox, Colombia, with its vibrant yellow facade, ornate bell tower, and bright red dome standing out against a clear blue sky.
FREE Experiences, Specialty Dining, Wi-Fi & More*
AmaWaterways' Logo.

7-night Wonders Of Colombia With 3-nights In Medellín, 2-nights In Cartagena Pre Cruise And 3-nights In Panama City Post Cruise Cruise/Land Package

Aboard

AmaMagdalena

From

Medellín, Colombia

Published prices from

$7,874

per person*

taxes & fees included

*Rates and offers are per person, in US Dollars, based on double occupancy, capacity controlled, subject to availability and confirmation, and may change without notice. Government taxes and fees are included. Rates and offers are available for select dates and categories only. Additional restrictions may apply. Call 1-800-377-9383 for full terms and conditions.

More to Explore

Cruise Lines

Holland America Line

AmaWaterways

Viking Ocean Cruises

Uniworld River Cruises

Windstar Cruises

Destinations

Transpacific

South American River

Bahamas

European River

U.S. Pacific Coast

Ports

Pistoia, Italy

Dakar, Senegal

Kolkata, India

Hydra, Greek Isle, Greece

Chau Doc, Vietnam

Cruise Ships

AmaDara

MSC Splendida

Viking Tonle

S.S. Beatrice

Caribbean Princess