22-night South America & Antarctica Holiday Cruise From Buenos Aires, Argentina

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A breathtaking view of the Strait of Magellan in Chile, with a small, forested island in the calm blue water and snow-capped mountains on the horizon.
Holland America's Oosterdam sailing in Alaska.
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Sailing Dec 19, 2026

from $5,179 per person* taxes and fees included

Your 22-night South America Cruise at a Glance

Sailings aboard Oosterdam depart from Buenos Aires, Argentina with 17 stops in ports-of-call including Strait of Magellan, Alley Glacier, and Canal Sarmiento. The Cruise Web can help you find the best deals and stateroom prices on the next sailing December 19, 2026.

Buenos Aires, the vibrant capital of Argentina, is a city full of energy, rich culture, and European-inspired architecture. Before you depart Buenos Aires, Argentina, we can help you plan travel and accommodations for your South America cruise.

Destination

South America

Stops on your South America voyage will include Montevideo on day 3 and Puerto Chacabuco on day 20. We can help you with excursions and making the most of any itinerary.

Cruise Ship

Oosterdam

Oosterdam, built in 2003 and refurbished in 2019, carries 1,964 passengers with a crew of 817. Ask us about dining options like Canaletto and entertainment like Cantare!

Amazing food and superb service make Holland America one of the longest running cruise lines. We can help you maximize deals on South America cruises aboard Oosterdam or 10 of Holland America’s other ships.