San Antonio, Santiago, Chile Cruise Deals

Plaza de Armas square in Santiago, Chile.

Upcoming San Antonio, Santiago, Chile Cruise Deals

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*Rates and offers are per person, in US Dollars, based on double occupancy, capacity controlled, subject to availability and confirmation, and may change without notice. Government taxes and fees are included. Rates and offers are available for select dates and categories only. Additional restrictions may apply. Call 1-800-377-9383 for full terms and conditions.

Modern building illuminated at sunset along the coast in Callao, Peru.

FREE $200 Shipboard Credit & More with Azamara Circle*+ 2 more offers

13-night Chile, Peru & Panama Voyage

Santiago (San Antonio)

Aboard

Azamara Quest

From

San Antonio, Santiago, Chile

1 Sailing

Mar 2, 2026

1 Sailing

Mar 2, 2026

Published prices from

$1,959

per person*

taxes & fees included

Panama City skyline from water.

Exclusive Onboard Savings, Events & Reduced Fares with Mariner Society*+ 1 more offer

17-night Inca & Panama Canal Discovery Cruise

Santiago (San Antonio)

General San Martin

Trujillo (Salaverry)

Aboard

Oosterdam

From

San Antonio, Santiago, Chile

1 Sailing

Mar 22, 2026

1 Sailing

Mar 22, 2026

Published prices from

$3,249

per person*

taxes & fees included

Overwater bungalows in Tahiti, French Polynesia.

Up to FREE $2,000 Onboard Credit*

19-night Easter & Pitcairn Islands: Marooned, Moai & Mutineers Cruise

Santiago (San Antonio)

Juan Fernandez Islands

Aboard

Seabourn Pursuit

From

San Antonio, Santiago, Chile

2 Sailings

Apr 2, 2026 - Apr 7, 2027

2 Sailings

Apr 2, 2026 - Apr 7, 2027

Published prices from

$14,999

per person*

taxes & fees included

Overwater bungalows in Tahiti, French Polynesia.

Up to FREE $2,000 Onboard Credit*

30-night Across Oceanic Cultures: Chilean Coast To Fiji Cruise

Santiago (San Antonio)

Juan Fernandez Islands

Aboard

Seabourn Pursuit

From

San Antonio, Santiago, Chile

1 Sailing

Apr 2, 2026

1 Sailing

Apr 2, 2026

Published prices from

$24,299

per person*

taxes & fees included

Plaza de Armas square in Santiago, Chile.

Exclusive Onboard Savings, Events & Reduced Fares with Mariner Society*

15-night South America Pathways: Chilean Fjords & Glaciers Cruise

Santiago (San Antonio)

Puerto Chacabuco

Aboard

Oosterdam

From

San Antonio, Santiago, Chile

1 Sailing

Dec 4, 2026

1 Sailing

Dec 4, 2026

Published prices from

$3,339

per person*

taxes & fees included

Plaza de Armas square in Santiago, Chile.

Exclusive Events, Experiences & More with Captain's Circle*+ 2 more offers

15-night Cape Horn & Glaciers of Patagonia Cruise

Santiago (San Antonio)

Aboard

Majestic Princess

From

San Antonio, Santiago, Chile

1 Sailing

Dec 22, 2026

1 Sailing

Dec 22, 2026

Published prices from

$3,856

per person*

taxes & fees included

Tropical beach with lounge chairs in Cozumel.

FREE $200 Shipboard Credit & More with Azamara Circle*+ 2 more offers

19-night Southern America & Panama Canal Voyage: Lima, Panama City & Cozumel

Santiago (San Antonio)

Aboard

Azamara Journey

From

San Antonio, Santiago, Chile

1 Sailing

Mar 10, 2027

1 Sailing

Mar 10, 2027

Published prices from

$7,169

per person*

taxes & fees included

A panoramic view of the rugged, green landscape of the Falkland Islands, with a low cloud covering the top of a hill and the blue sea in the foreground under a dramatic sky.

Exclusive Onboard Savings, Events & Reduced Fares with Mariner Society*+ 1 more offer

14-night South American Passage Cruise

Santiago (San Antonio)

Puerto Chacabuco

Canal Sarmiento

Aboard

Oosterdam

From

San Antonio, Santiago, Chile

1 Sailing

Dec 4, 2025

1 Sailing

Dec 4, 2025

A panoramic view of Nuku Island, a volcanic Marquesas island, with steep, lush green hills and a small village lining a harbor with sailboats at sunset.

Up to FREE $2,000 Onboard Credit*

56-night Remote Islands Of The Pacific & Kimberley Expedition Cruise

Santiago (San Antonio)

Juan Fernandez Islands

Aboard

Seabourn Pursuit

From

San Antonio, Santiago, Chile

1 Sailing

Apr 2, 2026

1 Sailing

Apr 2, 2026

Published prices from

$48,799

per person*

taxes & fees included

A panoramic view of the rugged, green landscape of the Falkland Islands, with a low cloud covering the top of a hill and the blue sea in the foreground under a dramatic sky.

Exclusive Events, Experiences & More with Captain's Circle*+ 2 more offers

16-night Cape Horn & Strait Of Magellan Cruise

Santiago (San Antonio)

Puerto Chacabuco

Aboard

Sapphire Princess

From

San Antonio, Santiago, Chile

1 Sailing

Dec 6, 2025

1 Sailing

Dec 6, 2025

Published prices from

$5,894

per person*

taxes & fees included

Panama City skyline from water.

Access Exclusive Savings with Cunard World Club*+ 3 more offers

Cunard

19-night 2027 World Voyage Segment: San Antonio To Fort Lauderdale

Santiago (San Antonio)

Aboard

Queen Anne

From

San Antonio, Santiago, Chile

1 Sailing

Feb 28, 2027

1 Sailing

Feb 28, 2027

Published prices from

$4,599

per person*

taxes & fees included

A breathtaking action shot of a killer whale breaching from the deep blue Antarctic waters, with a massive glacier and icebergs in the background.

Exclusive Onboard Savings, Events & Reduced Fares with Mariner Society*+ 1 more offer

22-night South America & Antarctica Cruise

Santiago (San Antonio)

Puerto Chacabuco

Aboard

Oosterdam

From

San Antonio, Santiago, Chile

2 Sailings

Jan 9, 2026 - Jan 10, 2027

2 Sailings

Jan 9, 2026 - Jan 10, 2027

Published prices from

$5,979

per person*

taxes & fees included

A serene waterside view of the historic wooden pier and colorful buildings lining the shore of Punta Arenas, Chile, during a calm and beautiful sunrise.

Exclusive Savings & Events with Oceania Club*+ 1 more offer

Oceania Cruises

20-night Antarctic Triumph Voyage

Santiago (San Antonio)

Puerto Chacabuco

Laguna San Rafael

Aboard

Marina

From

San Antonio, Santiago, Chile

1 Sailing

Dec 21, 2025

1 Sailing

Dec 21, 2025

Published prices from

$5,799

per person*

taxes & fees included

A close-up of a fluffy, young emperor penguin chick with its beak open, showcasing the unique wildlife of the Antarctic Peninsula.

Exclusive Savings & Events with Oceania Club*+ 1 more offer

Oceania Cruises

20-night Spectacular Antarctica Voyage

Santiago (San Antonio)

Puerto Chacabuco

Aboard

Marina

From

San Antonio, Santiago, Chile

1 Sailing

Feb 15, 2026

1 Sailing

Feb 15, 2026

Published prices from

$5,699

per person*

taxes & fees included

Peaceful sunrise over a sandy Florida beach with sea oats in Port Canaveral.

Access Exclusive Savings with Cunard World Club*+ 3 more offers

Cunard

33-night San Antonio To Southampton Cruise

Santiago (San Antonio)

Aboard

Queen Anne

From

San Antonio, Santiago, Chile

1 Sailing

Feb 28, 2027

1 Sailing

Feb 28, 2027

Published prices from

$6,449

per person*

taxes & fees included

A serene waterside view of the historic wooden pier and colorful buildings lining the shore of Punta Arenas, Chile, during a calm and beautiful sunrise.

Exclusive Events, Experiences & More with Captain's Circle*+ 2 more offers

21-night Iguazu Falls Adventure Cruisetour #1E

Santiago (San Antonio)

Puerto Chacabuco

Aboard

Sapphire Princess

From

San Antonio, Santiago, Chile

1 Sailing

Dec 6, 2025

1 Sailing

Dec 6, 2025

Published prices from

$7,429

per person*

taxes & fees included

A cruise ship navigating through the Gatun Locks of the Panama Canal, an important navigational route and popular tourist destination.

Access Exclusive Savings with Cunard World Club*+ 3 more offers

Cunard

36-night San Antonio To Hamburg Cruise

Santiago (San Antonio)

Aboard

Queen Anne

From

San Antonio, Santiago, Chile

1 Sailing

Feb 28, 2027

1 Sailing

Feb 28, 2027

Published prices from

$6,999

per person*

taxes & fees included

A view of a huge rock island covered in trees and another large rock in the foreground on the shore of Pentecost Island, Vanuatu, with a rainbow arching across the sky.

Up to FREE $2,000 Onboard Credit*

46-night Remote Islands Of The Pacific & New Guinea Cruise

Santiago (San Antonio)

Juan Fernandez Islands

Aboard

Seabourn Pursuit

From

San Antonio, Santiago, Chile

1 Sailing

Apr 2, 2026

1 Sailing

Apr 2, 2026

Published prices from

$34,199

per person*

taxes & fees included

A stunning view of the Patagonian fjords near Puerto Chacabuco, Chile, featuring calm blue water, lush green forested hills, and snow-capped mountains in the distance.

Give $250, Get $250*

Regent Seven Seas

16-night Edge of the World Expedition Cruise

Santiago (San Antonio)

Puerto Chacabuco

Laguna San Rafael

Aboard

Seven Seas Splendor

From

San Antonio, Santiago, Chile

1 Sailing

Feb 1, 2026

1 Sailing

Feb 1, 2026

Published prices from

$13,699

per person*

taxes & fees included

A huge colony of black and white king penguins gathered on a gravel beach, with a snow-covered mountain range and a wide stream in the background in South Georgia.

Up to FREE $2,000 Onboard Credit*

38-night Chilean Fjords, Antarctica, South Georgia & Falklands Cruise

Santiago (San Antonio)

Moraleda Channel

Darwin Channel & Fjords

Aboard

Seabourn Pursuit

From

San Antonio, Santiago, Chile

1 Sailing

Nov 4, 2026

1 Sailing

Nov 4, 2026

Published prices from

$40,098

per person*

taxes & fees included

A massive, stunning blue and white glacier in the Sarmiento Channel, Patagonia, Chile, with its dramatic crevasses and ice formations towering over the deep blue water.

Exclusive Onboard Savings, Events & Reduced Fares with Mariner Society*

14-night South America Pathways: Chilean Fjords & Glaciers Cruise

Santiago (San Antonio)

Puerto Chacabuco

Aboard

Oosterdam

From

San Antonio, Santiago, Chile

1 Sailing

Feb 23, 2027

1 Sailing

Feb 23, 2027

Published prices from

$3,224

per person*

taxes & fees included

A panoramic landscape view of the lush, green volcanic mountains and hills of Moorea, French Polynesia, with the Opunohu and Cook's Bays on either side.

Exclusive Onboard Savings, Events & Reduced Fares with Mariner Society*+ 1 more offer

41-night Grand World Voyage Cruise

Santiago (San Antonio)

Pitcairn Island

Aboard

Volendam

From

San Antonio, Santiago, Chile

1 Sailing

Feb 10, 2026

1 Sailing

Feb 10, 2026

Published prices from

$7,694

per person*

taxes & fees included

An aerial shot of the port city of Ushuaia, Argentina, at dusk, showing city lights along the Beagle Channel with the snow-capped Andes Mountains in the background.

Save up to 30% on Last Minute Sailings*+ 1 more offer

18-night Chilean Fjords & Antarctica Cruise

Santiago (San Antonio)

Moraleda Channel

Darwin Channel & Fjords

Aboard

Seabourn Pursuit

From

San Antonio, Santiago, Chile

2 Sailings

Nov 4, 2026 - Oct 18, 2027

2 Sailings

Nov 4, 2026 - Oct 18, 2027

Published prices from

$17,998

per person*

taxes & fees included

A large glacier on a mountain cliff, with a powerful waterfall cascading down into a fjord in the Chilean Fjords.

FREE Dining, Waterparks, Entertainment & More*+ 1 more offer

Carnival Cruise Line

14-night Journeys - South America Cruise

Santiago (San Antonio)

Darwin Channel & Fjords

Aboard

Carnival Firenze

From

San Antonio, Santiago, Chile

1 Sailing

Jan 19, 2027

1 Sailing

Jan 19, 2027

Published prices from

$1,754

per person*

taxes & fees included

A beautiful landscape of the Cockburn Channel, featuring a rainbow arching over a snow-capped mountain slope, while a grassy hillside descends to the calm turquoise water.

Exclusive Onboard Savings, Events & Reduced Fares with Mariner Society*+ 1 more offer

14-night South America Passage Cruise

Santiago (San Antonio)

Puerto Chacabuco

Canal Sarmiento

Aboard

Oosterdam

From

San Antonio, Santiago, Chile

1 Sailing

Feb 22, 2026

1 Sailing

Feb 22, 2026