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MSC Cruises: Kids Sail FREE on select sailings*
MSC Cruises Military Discount: up to 10% OFF*
MSC Cruises Mediterranean cruises from $69*
When it comes to MSC Cruises, Mediterranean cruises are their specialty. With European-style service, extensive knowledge of the area and attractions within, and regional touches that will bring a smile to your face, these vacation options are a true delight. Explore a region featuring castles, palaces, and quaint towns. Go on a culinary adventure in search of the finest fare—feasting upon seafood in Italy or puffy pastries in France. Enrich yourself with a salsa dancing lesson from a real ‘bailador’ or bask in the architectural excellence of Rome. Sail with the best on a MSC Cruises Mediterranean cruise.
View MSC Cruises to Mediterranean
The Mediterranean is one of the most creative and inspiring regions in the world. On an MSC Cruises sailing to the Mediterranean you can visit pyramids in Egypt, taste wine in Barcelona and learn about Greek gods in Athens.
Learn more about each of the possible departure ports for a Mediterranean cruise with MSC Cruises. Your MSC Cruises Mediterranean cruise could leave from any of the following cities:
Escape to this Mediterranean city of Alicante, Spain with enticing sandy beaches and museums.
A beautiful spot along the Adriatic Sea, Ancona offers cruisers an interesting take on Italian history, especially given its history as a Papal State.
Discover imaginative architecture, impressive Spanish dishes and beautiful excursions into nature when you cruise to Barcelona, the capital of Catalonia.
Cruise to Bari and explore this extraordinary city in the South of Italy. Highlights include its interesting history and friendly people, who are always ready to show you their way of life.
This ancient city is sure to charm with its immaculate architecture, tranquil harbor and coastline, delicious cuisine as well as its Greek-Italian feel.
As the second largest island in the Mediterranean, this island offers wonderful blue lagoons, ancient buildings, white sand beaches and rich culture.
Live the glamorous life in Cannes, the city in the South of France known as the host of the yearly Cannes Film Festival.
A cruise to Civitavecchia is a chance for you to hop a quick train to Rome and explore the enormous history through ruins, galleries and The Vatican museums.
Cruise to the historical port city of Genoa for a laid back walk through history in the city’s well-preserved streets, and be sure to try the local foods like pesto and focaccia bread.
Istanbul is a unique city that blends its two distinct influences – from its founding as the Christian capital of Constantinople to the Ottoman ruled Istanbul. Today you can discover both eras and the modern beauty in this thriving city.
Ismir is a bustling metropolitan center located in Western Turkey, surrounded by the waters of the Gulf of Izmir and the Gediz River.
Kusadasi welcomes visitors from all over to discover the ruins of the ancient city of Ephesus, a powerful city that was once home to the Virgin Mary.
Start your own artistic renaissance on a cruise to La Spezia, part of the beautiful coastal landscape of Northern Italy near Tuscany, Florence, Pisa and Livorno.
Lisbon has deep cultural roots that are exposed through ruins and museum artifacts. Cruise to Lisbon and discover the culture and history of Portugal in its capital city.
As a port city on the western coast of a country known for its magnificent art, the cruise port of Livorno, Italy is a great starting point to exploring the phenomenal paintings and sculptures found in Italy.
Cruise to Malaga, the celebrated home of Picasso, one of the modern era’s most influential artists. Other attractions include the beautiful Moorish castles and mesmerizing coastal cliffs.
Marseilles, France’s second most popular city, offers cruisers a vast landscape to discover the area’s ancient history and relish the more modern lifestyle of the French living off the coast of the Mediterranean.
Enjoy Messina, the gateway to Sicily, the largest island in the Mediterranean with a proud heritage and world renowned food.
In Miami, you’ll enjoy a small taste of the tropical weather many of you will experience during your cruise, and you’ll see why Miami is one of the most popular places to live in America.
Prepare your appetite if you plan to visit Naples, for it is home to many of Italy’s most famous culinary traditions. Naples is more than just great food, so make time to visit the beautiful cathedrals and enriching museums.
Sail into Olbia, Italy to experience a sunny taste of Italy's Emerald Coast with beautiful beaches, scenic islands and secluded coastal trails.
Explore the varied history and culture of Palermo, Sicily’s capital city, and enjoy its diverse history, culture and art.
The island of Mallorca can boast of an impressive port city where the old and new worlds dwell in perfect harmony.
Learn about the Greek gods and the early philosophy of Socrates when you visit the incredible ruins left in Athens, Greece. At night, go out and take in the culture with the modern Athenians.
Beaches, historic sites and a melting pot of cultures can be found in this delightful city along the Adriatic Coast.
Cruise to the mysterious city of Tarragonna, where ancient ruins and a spicy nightlight are the main attractions.
Sit back and enjoy the sea breezes in Trieste, an Italian city that despite being close to Venice is more akin to Vienna, the capital of the Hapsburg Empire.
Located on the Mediterranean Sea, Valencia is a city in Spain that attracts a lot of visitors to uncover the city’s past and revel in its modern achievements, most notably The City of Arts and Sciences.
This entire city is known as a UNESCO World Heritage Site leaving many historic areas and landmarks to explore during your visit to this impressive capital city.
Experience the serene, romantic splendor of Venice, but don’t forget to check out its wonderful museums and neighborhoods located off the Grand Canal.
View our photo gallery of Mediterranean cruising photos from MSC Cruises. Remember, this is only a taste of the experiences waiting for you on a MSC Cruises Mediterranean cruise vacation.
With an overwhelming world of choices, we understand you may need some personal assistance to plan your perfect vacation. From finding the right destination to choosing the best departure date, we're here to help. Plus, our experienced travel consultants have access to exclusive vacation deals to make sure you get the best value for your time and money.