Holland America Cruises to Panama Canal

Holland America Cruise Experience: Aerial view of their majestic ship transiting the iconic Panama Canal, framed by lush rainforest and mountains under blue sky.

Overview

Dreaming of a vacation that stands out from the rest? Experience a Panama Canal cruise with Holland America Line for a voyage filled with incredible cultural touches, special and memorable experiences, and both natural and man-made excellence. Relax on the serene beaches of the Panamanian coast, or give yourself a thrill filled with natural beauty with a zip line through the rainforest.

Explore intriguing ports-of-call in between, and then gaze in wonder and take a mental picture of the amazing experience that is a trip through the locks. Sound enticing? Join Holland America Line for a cruise to the Panama Canal

Upcoming Holland America Cruises to Panama Canal

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40 results

A serene aerial shot of Gatun Lake in Panama, featuring a large body of water surrounded by lush, green, forested islands and distant hills under a partly cloudy blue sky.

Up to 50% off + up to $800 Onboard Credit*

12-night Panama Canal Discovery Cruise: Costa Rica & Greater Antilles From Fort Lauderdale, Florida

Aboard

Nieuw Amsterdam

From

Fort Lauderdale, Florida

5 Sailings

Nov 8, 2026 - Mar 21, 2027

5 Sailings

Nov 8, 2026 - Mar 21, 2027

Published prices from

$1,759

per person*

taxes & fees included

A serene hiking path winds through a dense, lush green jungle with a towering tree on the left, capturing the essence of an adventure in nature.

Up to 50% off + up to $800 Onboard Credit*

21-night Panama Canal & Southern Caribbean Cruise: Abc Islands From Fort Lauderdale, Florida

Aboard

Nieuw Amsterdam

From

Fort Lauderdale, Florida

2 Sailings

Nov 8, 2026 - Mar 21, 2027

2 Sailings

Nov 8, 2026 - Mar 21, 2027

Published prices from

$2,659

per person*

taxes & fees included

Casa Rosada government building in Buenos Aires.

Up to $500 FREE Onboard Credit*+ 3 more offers

TCW EXCLUSIVE

31-night Panama Canal, Inca & South America: Chilean Fjords Cruise From Fort Lauderdale, Florida

Ft. Lauderdale

Grand Cayman (George Town)

Aboard

Oosterdam

From

Fort Lauderdale, Florida

1 Sailing

Nov 18, 2026

1 Sailing

Nov 18, 2026

A large flock of Guanay cormorants perched on the wooden posts of a pier at General San Martin Port in Peru, with the turquoise ocean and a control tower in the background.

Up to $500 FREE Onboard Credit*+ 3 more offers

TCW EXCLUSIVE

16-night Inca & Panama Canal Discovery: Lima Overnight Cruise From Fort Lauderdale, Florida

Ft. Lauderdale

Grand Cayman (George Town)

Aboard

Oosterdam

From

Fort Lauderdale, Florida

1 Sailing

Nov 18, 2026

1 Sailing

Nov 18, 2026

Published prices from

$2,039

per person*

taxes & fees included

Puntarenas, Costa Rica tropical landscape with palm trees and mountains.

Up to $500 FREE Onboard Credit*+ 4 more offers

TCW EXCLUSIVE

15-night Panama Canal Holiday Cruise From San Diego, California

Aboard

Zaandam

From

San Diego, California

2 Sailings

Dec 19, 2026 - Dec 18, 2027

2 Sailings

Dec 19, 2026 - Dec 18, 2027

Published prices from

$2,749

per person*

taxes & fees included

A panoramic shot of the colorful waterfront houses and palm trees of Key West, Florida, reflecting on the calm, turquoise water under a clear blue sky.

Up to $500 FREE Onboard Credit*+ 3 more offers

TCW EXCLUSIVE

19-night Panama Canal Holiday Cruise: Amber Cove & Costa Rica From Fort Lauderdale, Florida

Aboard

Nieuw Amsterdam

From

Fort Lauderdale, Florida

1 Sailing

Dec 20, 2026

1 Sailing

Dec 20, 2026

Published prices from

$2,169

per person*

taxes & fees included

Immaculate Conception Cathedral in Colon.

Up to $500 FREE Onboard Credit*+ 3 more offers

TCW EXCLUSIVE

12-night Panama Canal Holiday Cruise: Costa Rica & Greater Antilles From Fort Lauderdale, Florida

Aboard

Nieuw Amsterdam

From

Fort Lauderdale, Florida

1 Sailing

Dec 27, 2026

1 Sailing

Dec 27, 2026

Published prices from

$1,659

per person*

taxes & fees included

Oranjestad, Aruba harbor with boats and colorful Dutch architecture.

Up to $500 FREE Onboard Credit*+ 3 more offers

TCW EXCLUSIVE

21-night Panama Canal & Southern Caribbean Holiday Cruise From Fort Lauderdale, Florida

Aboard

Nieuw Amsterdam

From

Fort Lauderdale, Florida

2 Sailings

Dec 27, 2026 - Feb 7, 2027

2 Sailings

Dec 27, 2026 - Feb 7, 2027

Published prices from

$2,594

per person*

taxes & fees included

A golden sunset over the beach in Huatulco, Mexico, with footprints in the sand leading towards the shimmering ocean and a warm glow over the water.

Up to $500 FREE Onboard Credit*+ 3 more offers

TCW EXCLUSIVE

14-night Panama Canal Cruise From Miami, Florida

Aboard

Zuiderdam

From

Miami, Florida

1 Sailing

Jan 2, 2027

1 Sailing

Jan 2, 2027

Published prices from

$1,669

per person*

taxes & fees included

Modern building illuminated at sunset along the coast in Callao, Peru.

Up to $500 FREE Onboard Credit*+ 3 more offers

TCW EXCLUSIVE

41-night Grand South America & Antarctica Voyage From Fort Lauderdale, Florida

Ft. Lauderdale

Grand Cayman (George Town)

Aboard

Zaandam

From

Fort Lauderdale, Florida

1 Sailing

Jan 3, 2027

1 Sailing

Jan 3, 2027

Published prices from

$8,999

per person*

taxes & fees included

Up to $500 FREE Onboard Credit*+ 3 more offers

TCW EXCLUSIVE

70-night Grand South America & Antarctica Voyage From Fort Lauderdale, Florida

Ft. Lauderdale

Grand Cayman (George Town)

Aboard

Zaandam

From

Fort Lauderdale, Florida

1 Sailing

Jan 3, 2027

1 Sailing

Jan 3, 2027

Published prices from

$13,599

per person*

taxes & fees included

A panoramic view of Savusavu, Vanua Levu, Fiji, with a tranquil bay filled with sailboats, a lush green peninsula in the foreground, and mountainous terrain in the background.

Up to $500 FREE Onboard Credit*+ 3 more offers

TCW EXCLUSIVE

35-night Grand World Voyage From Fort Lauderdale, Florida

Aboard

Volendam

From

Fort Lauderdale, Florida

1 Sailing

Jan 5, 2027

1 Sailing

Jan 5, 2027

Published prices from

$7,999

per person*

taxes & fees included

Up to $500 FREE Onboard Credit*+ 3 more offers

TCW EXCLUSIVE

129-night Grand World Voyage Cruise From Fort Lauderdale, Florida

Aboard

Volendam

From

Fort Lauderdale, Florida

1 Sailing

Jan 5, 2027

1 Sailing

Jan 5, 2027

Published prices from

$28,009

per person*

taxes & fees included

Up to $500 FREE Onboard Credit*+ 3 more offers

TCW EXCLUSIVE

21-night Southern Caribbean & Panama Canal Cruise: Abc Islands From Fort Lauderdale, Florida

Aboard

Nieuw Amsterdam

From

Fort Lauderdale, Florida

2 Sailings

Jan 8 - Feb 19, 2027

2 Sailings

Jan 8 - Feb 19, 2027

Published prices from

$2,879

per person*

taxes & fees included

A wide-angle view of the bustling harbor of Charlotte Amalie, St. Thomas, with many sailboats and yachts docked in the tranquil blue water, and the town's buildings climbing the lush green hills.

Up to $500 FREE Onboard Credit*+ 3 more offers

TCW EXCLUSIVE

21-night Panama Canal & Eastern Caribbean Cruise: U.S. Virgin Islands From Fort Lauderdale, Florida

Aboard

Nieuw Amsterdam

From

Fort Lauderdale, Florida

2 Sailings

Jan 17 - Feb 28, 2027

2 Sailings

Jan 17 - Feb 28, 2027

Published prices from

$2,654

per person*

taxes & fees included

Up to $500 FREE Onboard Credit*+ 3 more offers

TCW EXCLUSIVE

21-night Eastern Caribbean & Panama Canal Cruise: U.S. Virgin Islands From Fort Lauderdale, Florida

Ft. Lauderdale

St. John's

St. Thomas (Charlotte Amalie)

Roadtown

San Juan

+10 more

Aboard

Nieuw Amsterdam

From

Fort Lauderdale, Florida

2 Sailings

Jan 29 - Mar 12, 2027

2 Sailings

Jan 29 - Mar 12, 2027

Published prices from

$2,644

per person*

taxes & fees included

An aerial view of the bustling city of Balboa, Panama, with a scenic coastal road alongside a marina and tall modern skyscrapers in the background.

Up to $500 FREE Onboard Credit*+ 3 more offers

TCW EXCLUSIVE

15-night Panama Canal Cruise From San Diego, California

Aboard

Zuiderdam

From

San Diego, California

1 Sailing

Jan 30, 2027

1 Sailing

Jan 30, 2027

Published prices from

$1,774

per person*

taxes & fees included

Up to $500 FREE Onboard Credit*+ 3 more offers

TCW EXCLUSIVE

31-night Panama Canal, Inca & South America: Chilean Fjords Cruise From Buenos Aires, Argentina

Aboard

Oosterdam

From

Buenos Aires, Argentina

1 Sailing

Mar 9, 2027

1 Sailing

Mar 9, 2027

Published prices from

$4,929

per person*

taxes & fees included

Up to $500 FREE Onboard Credit*+ 4 more offers

TCW EXCLUSIVE

14-night Panama Canal Cruise From Fort Lauderdale, Florida

Aboard

Zaandam

From

Fort Lauderdale, Florida

2 Sailings

Mar 14, 2027 - Jan 16, 2028

2 Sailings

Mar 14, 2027 - Jan 16, 2028

Published prices from

$1,469

per person*

taxes & fees included

A scenic panorama of the coastal city of Manta, Ecuador, with a densely packed urban area surrounded by lush green hills under a dramatic cloudy sky.

Up to $500 FREE Onboard Credit*+ 3 more offers

TCW EXCLUSIVE

16-night Inca & Panama Canal Discovery: Lima Overnight Cruise From San Antonio, Santiago, Chile

Santiago (San Antonio)

Aboard

Oosterdam

From

San Antonio, Santiago, Chile

1 Sailing

Mar 24, 2027

1 Sailing

Mar 24, 2027

Published prices from

$2,379

per person*

taxes & fees included

Golden Gate Bridge and San Francisco Bay.

Up to $500 FREE Onboard Credit*+ 3 more offers

TCW EXCLUSIVE

21-night Panama Canal Cruise From Fort Lauderdale, Florida

Aboard

Eurodam

From

Fort Lauderdale, Florida

1 Sailing

Apr 3, 2027

1 Sailing

Apr 3, 2027

Published prices from

$2,304

per person*

taxes & fees included

Up to $500 FREE Onboard Credit*+ 3 more offers

TCW EXCLUSIVE

20-night Panama Canal Cruise From Fort Lauderdale, Florida

Aboard

Eurodam

From

Fort Lauderdale, Florida

1 Sailing

Apr 3, 2027

1 Sailing

Apr 3, 2027

Published prices from

$2,204

per person*

taxes & fees included

Up to $500 FREE Onboard Credit*+ 3 more offers

TCW EXCLUSIVE

14-night Panama Canal Cruise From Fort Lauderdale, Florida

Aboard

Eurodam

From

Fort Lauderdale, Florida

1 Sailing

Apr 3, 2027

1 Sailing

Apr 3, 2027

Published prices from

$1,794

per person*

taxes & fees included

A scenic sunset over the iconic rock formations of Land's End, including El Arco, a major landmark of Cabo San Lucas, Mexico.

Up to $500 FREE Onboard Credit*+ 3 more offers

TCW EXCLUSIVE

21-night Panama Canal Cruise From Fort Lauderdale, Florida

Aboard

Nieuw Amsterdam

From

Fort Lauderdale, Florida

1 Sailing

Apr 11, 2027

1 Sailing

Apr 11, 2027

Published prices from

$2,204

per person*

taxes & fees included

Up to $500 FREE Onboard Credit*+ 3 more offers

TCW EXCLUSIVE

17-night Panama Canal Cruise From Fort Lauderdale, Florida

Aboard

Nieuw Amsterdam

From

Fort Lauderdale, Florida

1 Sailing

Apr 11, 2027

1 Sailing

Apr 11, 2027

Published prices from

$1,909

per person*

taxes & fees included

*Rates and offers are per person, in US Dollars, based on double occupancy, capacity controlled, subject to availability and confirmation, and may change without notice. Government taxes and fees are included. Rates and offers are available for select dates and categories only. Additional restrictions may apply. Call 1-800-377-9383 for full terms and conditions.

Holland America Cruises to Panama Canal

Upcoming Holland America Cruises to Panama Canal

12-night Panama Canal Discovery Cruise: Costa Rica & Greater Antilles From Fort Lauderdale, Florida

$1,759

21-night Panama Canal & Southern Caribbean Cruise: Abc Islands From Fort Lauderdale, Florida

$2,659

31-night Panama Canal, Inca & South America: Chilean Fjords Cruise From Fort Lauderdale, Florida

16-night Inca & Panama Canal Discovery: Lima Overnight Cruise From Fort Lauderdale, Florida

$2,039

15-night Panama Canal Holiday Cruise From San Diego, California

$2,749

19-night Panama Canal Holiday Cruise: Amber Cove & Costa Rica From Fort Lauderdale, Florida

$2,169

12-night Panama Canal Holiday Cruise: Costa Rica & Greater Antilles From Fort Lauderdale, Florida

$1,659

21-night Panama Canal & Southern Caribbean Holiday Cruise From Fort Lauderdale, Florida

$2,594

14-night Panama Canal Cruise From Miami, Florida

$1,669

41-night Grand South America & Antarctica Voyage From Fort Lauderdale, Florida

$8,999

70-night Grand South America & Antarctica Voyage From Fort Lauderdale, Florida

$13,599

35-night Grand World Voyage From Fort Lauderdale, Florida

$7,999

129-night Grand World Voyage Cruise From Fort Lauderdale, Florida

$28,009

21-night Southern Caribbean & Panama Canal Cruise: Abc Islands From Fort Lauderdale, Florida

$2,879

21-night Panama Canal & Eastern Caribbean Cruise: U.S. Virgin Islands From Fort Lauderdale, Florida

$2,654

21-night Eastern Caribbean & Panama Canal Cruise: U.S. Virgin Islands From Fort Lauderdale, Florida

$2,644

15-night Panama Canal Cruise From San Diego, California

$1,774

31-night Panama Canal, Inca & South America: Chilean Fjords Cruise From Buenos Aires, Argentina

$4,929

14-night Panama Canal Cruise From Fort Lauderdale, Florida

$1,469

16-night Inca & Panama Canal Discovery: Lima Overnight Cruise From San Antonio, Santiago, Chile

$2,379

21-night Panama Canal Cruise From Fort Lauderdale, Florida

$2,304

20-night Panama Canal Cruise From Fort Lauderdale, Florida

$2,204

14-night Panama Canal Cruise From Fort Lauderdale, Florida

$1,794

21-night Panama Canal Cruise From Fort Lauderdale, Florida

$2,204

17-night Panama Canal Cruise From Fort Lauderdale, Florida

$1,909

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