Top Destinations Departing from United States Ports
Published August 4, 2023
Updated August 14, 2025
Travel Experts
at The Cruise Web


There's no doubt that cruising to far-off corners of the world is incredibly tempting, but sometimes, the allure of exploring captivating destinations close to home is equally irresistible. If you're seeking extraordinary cruise experiences without the need to fly out of the continental United States, you're in for a treat!
In this extensive blog, we'll delve into seven immensely popular sailings, each offering a unique adventure right from U.S. ports. From the icy wilderness of Alaska to the tropical paradise of Hawaii, the enchanting Caribbean, and beyond, these cool cruises promise unforgettable memories. So, let's set sail and explore these marvelous voyages, complete with two exciting activities for cruisers at each destination.
Hawaii out of L.A.: Exploring the Aloha State
No need to board a plane to immerse yourself in the wonders of the "Aloha State" and its diverse islands. Departing from Los Angeles, embark on a magnificent journey to Hawaii, where enchanting experiences await. After four leisurely days at sea, you'll arrive in paradise with a plethora of activities to choose from!
Activities on a Hawaii Cruise

Hiking & Exploring Volcanoes & Waterfalls
Hawaii boasts an extraordinary landscape with active volcanoes and stunning waterfalls. Embark on guided hikes to witness the volcanic splendor and natural beauty up close.
Surfing Lessons & Traditional Luaus
Embrace the spirit of Hawaii by catching some waves with surfing lessons or savoring a traditional luau featuring Polynesian dances and a feast of local delicacies.
Alaska out of Seattle: The Untamed Frontier Awaits
Embark on a bucket-list journey to Alaska, "The Last Frontier," and discover the untamed beauty of this majestic wilderness. Depart from Seattle and prepare for an awe-inspiring adventure featuring extraordinary encounters with nature.
Activities on an Alaska Cruise

Whale Watching & Wildlife Spotting
Alaska's pristine waters are home to a breathtaking array of marine life. Keep your eyes peeled for magnificent humpback whales and other wildlife, such as eagles and seals.
Glacier Viewing & Salmon Feast
Witness the grandeur of massive glaciers as they calve into the sea with a resounding roar. Savor the freshest catch with a delectable feast of salmon, a local delicacy.
View Alaska Cruises from Seattle.
Southern Caribbean out of Fort Lauderdale: Bask in Tropical Paradise
For years, the Caribbean has reigned as the world's most popular cruise region, and the Southern Caribbean boasts some of its most alluring destinations. Depart from Fort Lauderdale and indulge in the perfect blend of sun, sand, and serenity!
Southern Caribbean Cruise Activities

Beach Bliss & Snorkeling Adventures
The Southern Caribbean is renowned for its pristine beaches and crystal-clear waters. Spend a day unwinding on the sandy shores or snorkeling among vibrant coral reefs.
Explore ABC Islands & Cultural Delights
Choose itineraries that include visits to the ABC islands of Aruba, Curaçao, and Bonaire, each offering a unique blend of Caribbean charm and rich cultural heritage.
View Southern Caribbean Cruises from Fort Lauderdale.
Panama Canal out of San Francisco: A Historic Engineering Marvel
Embark on a historic journey through the legendary Panama Canal, a 48-mile-long feat of engineering that connects the Atlantic and Pacific Oceans. Depart from San Francisco and traverse through history with fascinating activities.
Panama Canal Cruise Activities

Panama Canal Transit & Historical Insights
Witness the marvels of the Panama Canal as your ship navigates through a series of impressive locks. Learn about the canal's history and significance from onboard experts.
Explore Vibrant Ports of Central America
Immerse yourself in the vibrant cultures, colorful wildlife, and picturesque landscapes of ports in California, Mexico, and Central America, including Costa Rica, Panama, and Guatemala.
View Panama Canal Cruises from San Francisco.
Canada & New England out of NYC: Coastal Charms & Culinary Delights
Calling all lobster lovers, leaf-peepers, and history buffs! These cruises along the Northeast's rocky coastline are a true delight. Depart from NYC and savor the enchanting experiences and culinary delights.
Activities on a Canada & New England Cruise

Explore Historic Ports & Lighthouses
Delve into the region's rich maritime heritage by visiting historic ports like Boston and Bar Harbor. Admire the picturesque lighthouses that have guided sailors for generations.
Indulge in Lobster Feasts & Autumn Foliage Tours
Savor succulent lobster rolls and immerse yourself in the vibrant hues of autumn with foliage tours, a must during the fall season.
View Canada and New England Cruises from New York.
Bermuda out of Baltimore: A Picturesque Island Paradise
Bermuda, a pristine island paradise, beckons with its moderate climate and natural wonders. Set sail from Baltimore and discover the island's captivating history and thrilling activities.
Bermuda Cruise Activities

Historical Exploration of St. George
Stroll through the charming town of St. George, a UNESCO World Heritage Site, and immerse yourself in its rich colonial history and fascinating architecture.
Scuba Diving & Cave Exploration
Dive into Bermuda's crystal-clear waters and explore vibrant coral reefs teeming with marine life. Venture into mysterious caves for an extraordinary underground adventure.
View Bermuda Cruises from Baltimore.
Pacific Coast out of San Diego: Coastal Wonders & Wine Tasting
Embark on a remarkable cruise that explores the stunning coastal regions of California, the Pacific Northwest, and British Columbia, Canada. Wine enthusiasts, in particular, will find this voyage especially delightful!
Pacific Coast Cruise Activities

Coastal Sightseeing & Cultural Gems
Discover the beauty of California's coastline with visits to Monterey, Santa Barbara, and Catalina Island. Explore these charming towns, each with its unique cultural gems.
Wine Tours & Tastings
Delight in the region's renowned vineyards with curated wine tours and tastings, savoring world-famous wines amidst breathtaking scenery.
Pacific Coast Cruises from San Diego.
In conclusion, there are many destinations to explore, with no need for a passport in some cases, and unique voyages are well within your reach, right from the USA!
Whether you dream of exploring tropical paradises, witnessing majestic glaciers, basking in the Caribbean's warmth, or journeying through historic canals, these extraordinary cruises offer it all. So, set sail and create unforgettable memories that will last a lifetime.
For more information on any of the destinations mentioned above or to learn where else in the world you can have a once-in-a-lifetime cruise vacation, visit cruiseweb.com or call our experts at 1-800-377-9383! Bon voyage!


