Royal Caribbean Cruises from Colon, Panama

Immaculate Conception Cathedral in Colon.

Upcoming Royal Caribbean Cruises from Colon, Panama

7 Results

Taxes and fees included in all prices shown

Sort

Immaculate Conception Cathedral in Colon.

Up to $500 FREE Onboard Credit*+ 2 more offers

7-night Southern Caribbean Cruise

Cartagena (Colombia)

Aboard

Serenade of the Seas

From

Colon, Panama

12 Sailings

Jan 24 - Apr 11, 2026

12 Sailings

Jan 24 - Apr 11, 2026

Published prices from

$1,364

per person*

taxes & fees included

Colorful colonial balconies in Cartagena.

Up to $500 FREE Onboard Credit*+ 2 more offers

1-night Southern Caribbean Cruise

Cartagena (Colombia)

Aboard

Serenade of the Seas

From

Colon, Panama

1 Sailing

Apr 18, 2026

1 Sailing

Apr 18, 2026

Published prices from

$158

per person*

taxes & fees included

Immaculate Conception Cathedral in Colon.

Up to $500 FREE Onboard Credit*+ 2 more offers

10-night Panama Canal Westward Cruise

Puerto Vallarta

Aboard

Serenade of the Seas

From

Colon, Panama

1 Sailing

Apr 25, 2026

1 Sailing

Apr 25, 2026

Published prices from

$898

per person*

taxes & fees included

Oranjestad, Aruba harbor with boats and colorful Dutch architecture.

Up to $500 FREE Onboard Credit*+ 2 more offers

7-night Southern Caribbean Cruise

Cartagena (Colombia)

Aboard

Grandeur of the Seas

From

Colon, Panama

63 Sailings

May 9, 2026 - Apr 22, 2028

63 Sailings

May 9, 2026 - Apr 22, 2028

Published prices from

$729

per person*

taxes & fees included

Oranjestad, Aruba harbor with boats and colorful Dutch architecture.

Up to $500 FREE Onboard Credit*+ 2 more offers

10-night Southern Caribbean Cruise

Aboard

Grandeur of the Seas

From

Colon, Panama

1 Sailing

Nov 14, 2026

1 Sailing

Nov 14, 2026

Published prices from

$1,223

per person*

taxes & fees included

Oranjestad, Aruba harbor with boats and colorful Dutch architecture.

Up to $500 FREE Onboard Credit*+ 2 more offers

7-night Southern Caribbean Holiday Cruise

Cartagena (Colombia)

Aboard

Grandeur of the Seas

From

Colon, Panama

3 Sailings

Dec 19, 2026 - Dec 25, 2027

3 Sailings

Dec 19, 2026 - Dec 25, 2027

Published prices from

$1,080

per person*

taxes & fees included

A stunning panoramic view of Road Town on Tortola, British Virgin Islands, showing the harbor filled with boats and a small town surrounded by lush green hills overlooking the Caribbean Sea.

Up to $500 FREE Onboard Credit*+ 1 more offer

7-night Colon To San Juan Cruise

St. Vincent (Kingstown)

Aboard

Grandeur of the Seas

From

Colon, Panama

1 Sailing

Apr 24, 2027

1 Sailing

Apr 24, 2027

Published prices from

$853

per person*

taxes & fees included

*Rates and offers are per person, in US Dollars, based on double occupancy, capacity controlled, subject to availability and confirmation, and may change without notice. Government taxes and fees are included. Rates and offers are available for select dates and categories only. Additional restrictions may apply. Call 1-800-377-9383 for full terms and conditions.