Popular South America Cruises 2025 - Premium Cruise Lines

*Rates and offers are per person, in US Dollars, based on double occupancy, capacity controlled, subject to availability and confirmation, and may change without notice. Government taxes and fees are included. Rates and offers are available for select dates and categories only. Additional restrictions may apply. Call 1-800-377-9383 for full terms and conditions.

Popular South America Cruises

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7-night Southern Caribbean Cruise

$1,037

11-night Quito and Galápagos Inner Loop Cruise/Land Package

12-night Panama Canal With Costa Rica & Caribbean Cruise

$1,640

15-night Portugal, Argentina Transatlantic Cruise

$2,856

7-night Southern Caribbean Cruise

$833

12-night Panama Canal With Costa Rica & Caribbean Holiday Cruise

$1,979

11-night Quito and Galápagos Outer Loop Cruise/Land Package

10-night Panama Canal Cruise: Mexico, Belize & Costa Rica

$700

7-night Galapagos Inner Loop Cruise

$8,833

7-night Galapagos Outer Loop Cruise

$7,756

27-night Amazon Explorer Cruise

$5,709

20-night Andes & South America Cruise

$3,333

16-night Galápagos Outer Loop and Machu Picchu Cruise/Land Package

22-night Machu Picchu Explorer Cruisetour #2E

$7,729

16-night Galápagos Inner Loop and Machu Picchu Cruise/Land Package

11-night Panama Canal Cruise: Mexico, Costa Rica & Belize

$729

14-night Carnival Journeys - Panama Canal Cruise

$1,209

30-night Amazon Explorer Cruise

10-night Quito and Galápagos Inner Loop Cruise/Land Package

17-night Panama Canal & Inca Discovery Cruise

$2,616

36-night Andes & Cape Horn Grand Adventure Cruise

$9,422

31-night Panama Canal, Inca & South America Discovery Cruise

10-night Quito and Galápagos Outer Loop Cruise/Land Package

53-night Ultimate Antarctica & South America Adventure Cruise

$8,702

26-night Machu Picchu Explorer Cruisetour #2D

$7,399