

7-night Southern Caribbean Cruise
Aboard
Serenade of the Seas
From
Colon, Panama
18 Sailings
Nov 15, 2025 - Apr 11, 2026
18 Sailings
Nov 15, 2025 - Apr 11, 2026
Published prices from
$833
per person*
taxes & fees included


12 Results
Taxes and fees included in all prices shown
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Aboard
Serenade of the Seas
From
Colon, Panama
18 Sailings
Nov 15, 2025 - Apr 11, 2026
18 Sailings
Nov 15, 2025 - Apr 11, 2026
Published prices from
per person*
taxes & fees included


Aboard
Serenade of the Seas
From
Colon, Panama
1 Sailing
Dec 6, 2025
1 Sailing
Dec 6, 2025


Aboard
Serenade of the Seas
From
Colon, Panama
1 Sailing
Dec 12, 2025
1 Sailing
Dec 12, 2025
Published prices from
per person*
taxes & fees included


Aboard
Serenade of the Seas
From
Colon, Panama
2 Sailings
Dec 20 - Dec 27, 2025
2 Sailings
Dec 20 - Dec 27, 2025
Published prices from
per person*
taxes & fees included


Aboard
Serenade of the Seas
From
Cartagena, Colombia
2 Sailings
Dec 21 - Dec 28, 2025
2 Sailings
Dec 21 - Dec 28, 2025
Published prices from
per person*
taxes & fees included


Aboard
Serenade of the Seas
From
Colon, Panama
1 Sailing
Apr 18, 2026
1 Sailing
Apr 18, 2026
Published prices from
per person*
taxes & fees included


Aboard
Serenade of the Seas
From
Cartagena, Colombia
1 Sailing
Apr 19, 2026
1 Sailing
Apr 19, 2026
Published prices from
per person*
taxes & fees included


Aboard
Grandeur of the Seas
From
Colon, Panama
43 Sailings
May 9, 2026 - Apr 17, 2027
43 Sailings
May 9, 2026 - Apr 17, 2027
Published prices from
per person*
taxes & fees included


Aboard
Grandeur of the Seas
From
Cartagena, Colombia
40 Sailings
May 10, 2026 - Apr 11, 2027
40 Sailings
May 10, 2026 - Apr 11, 2027
Published prices from
per person*
taxes & fees included


Aboard
Grandeur of the Seas
From
Cartagena, Colombia
2 Sailings
Nov 8, 2026 - Apr 18, 2027
2 Sailings
Nov 8, 2026 - Apr 18, 2027
Published prices from
per person*
taxes & fees included


Aboard
Grandeur of the Seas
From
Colon, Panama
2 Sailings
Dec 19 - Dec 26, 2026
2 Sailings
Dec 19 - Dec 26, 2026
Published prices from
per person*
taxes & fees included


Aboard
Grandeur of the Seas
From
Cartagena, Colombia
2 Sailings
Dec 20 - Dec 27, 2026
2 Sailings
Dec 20 - Dec 27, 2026
Published prices from
per person*
taxes & fees included
*Rates and offers are per person, in US Dollars, based on double occupancy, capacity controlled, subject to availability and confirmation, and may change without notice. Government taxes and fees are included. Rates and offers are available for select dates and categories only. Additional restrictions may apply. Call 1-800-377-9383 for full terms and conditions.
Cruise Lines

Overview
A Royal Caribbean International cruise to South America is a grand adventure, sailing through a continent of stunning contrasts, from the iconic urban energy of its capital cities to the breathtaking natural wonders of Patagonia and the Amazon. These voyages are designed to provide a vacation that blends exhilarating onboard activities with unique, destination-rich experiences. The itineraries often span multiple weeks, allowing for deep, immersive exploration of this diverse continent.
The voyages offer a spectacular array of ports, including the vibrant hubs of Buenos Aires and Rio de Janeiro, the historical port of Cartagena, and the unique, remote destinations of the Chilean Fjords and Argentina's southernmost cities. This is a journey that reveals the heart and soul of South America, allowing you to immerse yourself in the local culture, witness incredible wildlife, and explore some of the world's most magnificent landscapes.
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