15-night Panama Canal Cruise From San Diego, California

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An aerial view of the bustling city of Balboa, Panama, with a scenic coastal road alongside a marina and tall modern skyscrapers in the background.
Holland America's Zuiderdam ship at sea.
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Sailing Jan 30, 2027

from $1,999 per person* taxes and fees included

Your 15-night Mexico Cruise at a Glance

Sailings aboard Zuiderdam depart from San Diego, California with 11 stops in ports-of-call including Half Moon Cay, Miami, and Cartagena (Colombia). The Cruise Web can help you find the best deals and stateroom prices on the next sailing January 30, 2027.

Departure Port

San Diego, California

San Diego, California is a sun-soaked coastal city known for its laid-back vibe, scenic beaches, and rich mix of history, culture, and outdoor fun. Before you depart San Diego, California, we can help you plan travel and accommodations for your Mexico cruise.

Destination

Mexico

Stops on your Mexico voyage will include Chiapas on day 7 and Puerto Quetzal on day 8. We can help you with excursions and making the most of any itinerary.

Cruise Ship

Zuiderdam

Zuiderdam, built in 2002 and refurbished in 2017, carries 1,964 passengers with a crew of 840. Ask us about dining options like Dive In and entertainment like Step One!

Amazing food and superb service make Holland America one of the longest running cruise lines. We can help you maximize deals on Mexico cruises aboard Zuiderdam or 10 of Holland America’s other ships.