7-night Wonders Of Colombia with 3-nights in Panama City Post-Cruise Cruise/Land Package From Cartagena, Colombia

AmaWaterways' Logo.

A beautiful colonial-era church in Mompox, Colombia, with its vibrant yellow facade, ornate bell tower, and bright red dome standing out against a clear blue sky.
Amawaterways AmaMelodia river ship exterior.
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Sailing Aug 12, 2026 - Jun 16, 2027

Your 10-night South America Cruise at a Glance

Sailings aboard AmaMelodia depart from Cartagena, Colombia with 7 stops in ports-of-call including Panama City, Barranquilla, and Calamar. The Cruise Web can help you find the best deals and stateroom prices on any of the 15 upcoming sailings in 2026 and 2027.

Departure Port

Cartagena, Colombia

Cartagena is a vibrant coastal city where history, Caribbean charm, and lively culture come together. Before you depart Cartagena, Colombia, we can help you plan travel and accommodations for your South America cruise.

Destination

South America

Stops on your South America voyage will include Calamar on day 2 and Magangue on day 3. We can help you with excursions and making the most of any itinerary.

Cruise Ship

AmaMelodia

AmaMelodia, built in 2024, carries 64 passengers with a crew of 30.

Cruise Line

AmaWaterways

Explore the world’s most beautiful rivers, creating a lifetime of memories from AmaWaterways’ intimate, luxurious river ships. We can help you maximize deals on South America cruises aboard AmaMelodia or 33 of AmaWaterways’s other ships.