Regent Cruises from Panama City, Panama

Modern Panama City skyline with skyscrapers.

Upcoming Regent Cruises from Panama City, Panama

6 Results

Taxes and fees included in all prices shown

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Hollywood sign on hills of Los Angeles.

Up to $500 FREE Onboard Credit*+ 1 more offer

28-night Canal To Coral Reefs Cruise

Puerto Vallarta

Aboard

Seven Seas Splendor

From

Panama City, Panama

1 Sailing

Jan 26, 2027

1 Sailing

Jan 26, 2027

Published prices from

$20,999

per person*

taxes & fees included

A close-up of vibrant, traditional Mayan textiles from Santo Tomás de Castilla, Guatemala, featuring intricate, colorful hand-embroidered floral patterns on a dark fabric.

Up to $500 FREE Onboard Credit*+ 1 more offer

11-night Crescent Beaches & Colorful Towns Cruise

Aboard

Seven Seas Prestige

From

Panama City, Panama

1 Sailing

Feb 22, 2027

1 Sailing

Feb 22, 2027

Published prices from

$7,499

per person*

taxes & fees included

A beautiful seaside view of the Farol da Barra lighthouse and the historic Fort of Santo Antônio da Barra, a major landmark in Santarém, Brazil, with the Atlantic Ocean and a rocky coastline in the foreground.

Up to $500 FREE Onboard Credit*+ 1 more offer

22-night Journey To The Amazon Cruise

Aboard

Seven Seas Grandeur

From

Panama City, Panama

1 Sailing

Mar 9, 2027

1 Sailing

Mar 9, 2027

Published prices from

$15,149

per person*

taxes & fees included

Modern Panama City skyline with skyscrapers.

Up to $500 FREE Onboard Credit*+ 1 more offer

14-night Carnival Of Caribbean Colors Cruise

Cartagena (Colombia)

Aboard

Seven Seas Grandeur

From

Panama City, Panama

1 Sailing

Mar 31, 2027

1 Sailing

Mar 31, 2027

Published prices from

$8,749

per person*

taxes & fees included

Colorful colonial balconies in Cartagena.

Up to $500 FREE Onboard Credit*+ 1 more offer

26-night Azure To Iberia Cruise

Cartagena (Colombia)

Aboard

Seven Seas Prestige

From

Panama City, Panama

1 Sailing

Mar 14, 2028

1 Sailing

Mar 14, 2028

Published prices from

$15,799

per person*

taxes & fees included

Oranjestad, Aruba harbor with boats and colorful Dutch architecture.

Up to $500 FREE Onboard Credit*+ 1 more offer

12-night Bon Bini Aruba Cruise

Cartagena (Colombia)

Aboard

Seven Seas Prestige

From

Panama City, Panama

1 Sailing

Mar 14, 2028

1 Sailing

Mar 14, 2028

Published prices from

$8,099

per person*

taxes & fees included

*Rates and offers are per person, in US Dollars, based on double occupancy, capacity controlled, subject to availability and confirmation, and may change without notice. Government taxes and fees are included. Rates and offers are available for select dates and categories only. Additional restrictions may apply. Call 1-800-377-9383 for full terms and conditions.