22-night Journey To The Amazon Cruise From Panama City, Panama

Regent Seven Seas Cruises.

An aerial view of a sandbar in Alter do Chão, Brazil, with a few small huts and boats, surrounded by the clear, calm waters of the Tapajós River.
Regent Seven Seas Grandeur cruise ship exterior
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Sailing Mar 9, 2027

from $22,049 per person* taxes and fees included

Your 22-night Caribbean Cruise at a Glance

Sailings aboard Seven Seas Grandeur depart from Panama City, Panama with 9 stops in ports-of-call including St. George's, Grenada, Oranjestad, Aruba, and Port of Spain. The Cruise Web can help you find the best deals and stateroom prices on the next sailing March 9, 2027.

Departure Port

Panama City, Panama

Panama City, Panama is a dynamic capital where gleaming skyscrapers meet colonial charm, all set against the backdrop of the world-famous Panama Canal. Before you depart Panama City, Panama, we can help you plan travel and accommodations for your Caribbean cruise.

Destination

Caribbean

Stops on your Caribbean voyage will include Panama Canal on day 2 and Manaus (Amazon River) on day 11. We can help you with excursions and making the most of any itinerary.

Seven Seas Grandeur, built in 2020, carries 744 passengers with a crew of 548. Ask us about dining options like The Study and entertainment like Card Room!

Offering a completely all-inclusive cruise, Regent Seven Seas is known for exquisite service on beautifully designed intimate ships, classic cruising at its best. We can help you maximize deals on Caribbean cruises aboard Seven Seas Grandeur or 6 of Regent’s other ships.