Colon, Panama Cruise Deals

Immaculate Conception Cathedral in Colon.

Upcoming Colon, Panama Cruise Deals

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*Rates and offers are per person, in US Dollars, based on double occupancy, capacity controlled, subject to availability and confirmation, and may change without notice. Government taxes and fees are included. Rates and offers are available for select dates and categories only. Additional restrictions may apply. Call 1-800-377-9383 for full terms and conditions.

Immaculate Conception Cathedral in Colon.

FREE All-Inclusive Package Upgrade*+ 1 more offer

Windstar

7-night Costa Rica & Panama Canal Cruise

Golfo Dulce (Puerto Jimenez)

Aboard

Wind Spirit

From

Colon, Panama

1 Sailing

Nov 29, 2025

1 Sailing

Nov 29, 2025

Immaculate Conception Cathedral in Colon.

FREE Dining, Onboard Activities & More*

6-night Southern Caribbean Cruise

Cartagena (Colombia)

Aboard

Serenade of the Seas

From

Colon, Panama

1 Sailing

Dec 6, 2025

1 Sailing

Dec 6, 2025

Oranjestad, Aruba harbor with boats and colorful Dutch architecture.

FREE Dining, Onboard Activities & More*

7-night Southern Caribbean Holiday Cruise

Cartagena (Colombia)

Aboard

Grandeur of the Seas

From

Colon, Panama

2 Sailings

Dec 19 - Dec 26, 2026

2 Sailings

Dec 19 - Dec 26, 2026

Published prices from

$1,149

per person*

taxes & fees included

Oranjestad, Aruba harbor with boats and colorful Dutch architecture.

FREE Dining, Onboard Activities & More*

7-night Southern Caribbean Holiday Cruise

Cartagena (Colombia)

Aboard

Serenade of the Seas

From

Colon, Panama

2 Sailings

Dec 20 - Dec 27, 2025

2 Sailings

Dec 20 - Dec 27, 2025

Colorful colonial balconies in Cartagena.

FREE Dining, Onboard Activities & More*

8-night Southern Caribbean Cruise

Cartagena (Colombia)

Aboard

Serenade of the Seas

From

Colon, Panama

1 Sailing

Dec 12, 2025

1 Sailing

Dec 12, 2025

Published prices from

$1,398

per person*

taxes & fees included

Oranjestad, Aruba harbor with boats and colorful Dutch architecture.

FREE All-Inclusive Package Upgrade*+ 1 more offer

Windstar

7-night Enchanting Colombia And Panamanian Islands Cruise

San Blas Islands

Cartagena (Colombia)

Aboard

Wind Spirit

From

Colon, Panama

1 Sailing

Dec 13, 2025

1 Sailing

Dec 13, 2025

Colorful colonial balconies in Cartagena.

FREE Dining, Onboard Activities & More*

1-night Southern Caribbean Cruise

Cartagena (Colombia)

Aboard

Serenade of the Seas

From

Colon, Panama

1 Sailing

Apr 18, 2026

1 Sailing

Apr 18, 2026

Published prices from

$153

per person*

taxes & fees included

Immaculate Conception Cathedral in Colon.

FREE Dining, Onboard Activities & More*

10-night Panama Canal Westward Cruise

Puerto Vallarta

Aboard

Serenade of the Seas

From

Colon, Panama

1 Sailing

Apr 25, 2026

1 Sailing

Apr 25, 2026

Published prices from

$1,150

per person*

taxes & fees included

Oranjestad, Aruba harbor with boats and colorful Dutch architecture.

FREE Dining, Onboard Activities & More*

7-night Southern Caribbean Cruise

Cartagena (Colombia)

Aboard

Grandeur of the Seas

From

Colon, Panama

43 Sailings

May 9, 2026 - Apr 17, 2027

43 Sailings

May 9, 2026 - Apr 17, 2027

Published prices from

$824

per person*

taxes & fees included

Oranjestad, Aruba harbor with boats and colorful Dutch architecture.

FREE Dining, Onboard Activities & More*

10-night Southern Caribbean Cruise

Aboard

Grandeur of the Seas

From

Colon, Panama

1 Sailing

Nov 14, 2026

1 Sailing

Nov 14, 2026

Published prices from

$1,318

per person*

taxes & fees included

Immaculate Conception Cathedral in Colon.

FREE Champagne, Entertainment, Dining & More*

Windstar

7-night Costa Rica & Panama Canal Cruise

Golfo Dulce (Puerto Jimenez)

Aboard

Wind Star

From

Colon, Panama

3 Sailings

Dec 5, 2026 - Jan 2, 2027

3 Sailings

Dec 5, 2026 - Jan 2, 2027

National Theatre of Costa Rica in San José.

FREE Champagne, Entertainment, Dining & More*

Windstar

10-night Monteverde Cloud Forest & Arenal Volcano Cruise/Land Package

Golfo Dulce (Puerto Jimenez)

Aboard

Wind Star

From

Colon, Panama

3 Sailings

Dec 5, 2026 - Jan 2, 2027

3 Sailings

Dec 5, 2026 - Jan 2, 2027

Immaculate Conception Cathedral in Colon.

FREE Dining, Onboard Activities & More*

7-night Southern Caribbean Cruise

Cartagena (Colombia)

Aboard

Serenade of the Seas

From

Colon, Panama

19 Sailings

Nov 8, 2025 - Apr 11, 2026

19 Sailings

Nov 8, 2025 - Apr 11, 2026

Published prices from

$833

per person*

taxes & fees included

An aerial view of the bustling city of Balboa, Panama, with a scenic coastal road alongside a marina and tall modern skyscrapers in the background.

FREE Champagne, Entertainment, Dining & More*

Windstar

7-night Costa Rica & Panama Canal Cruise

Golfo Dulce (Puerto Jimenez)

Aboard

Star Seeker

From

Colon, Panama

1 Sailing

Apr 13, 2026

1 Sailing

Apr 13, 2026

An aerial view of Bocas del Toro, a vibrant town on the Caribbean coast of Panama, featuring colorful houses built over clear blue water and numerous sailboats docked nearby.

FREE All-Inclusive Package Upgrade*+ 1 more offer

Windstar

6-night Panama’s Pristine Caribbean Cruise

San Blas Islands

Cartagena (Colombia)

Aboard

Star Pride

From

Colon, Panama

1 Sailing

Mar 9, 2026

1 Sailing

Mar 9, 2026

A cruise ship navigating through the Gatun Locks of the Panama Canal, an important navigational route and popular tourist destination.

FREE All-Inclusive Package Upgrade*+ 1 more offer

Windstar

11-night Monteverde Cloud Forest & Arenal Volcano Cruise/Land Package

Golfo Dulce (Puerto Jimenez)

Aboard

Wind Spirit

From

Colon, Panama

1 Sailing

Nov 29, 2025

1 Sailing

Nov 29, 2025

A scenic sunset over the iconic rock formations of Land's End, including El Arco, a major landmark of Cabo San Lucas, Mexico.

Exclusive Savings & Events with Oceania Club*+ 1 more offer

Oceania Cruises

12-night Pacific Pathways Voyage

Aboard

Regatta

From

Colon, Panama

1 Sailing

Nov 14, 2025

1 Sailing

Nov 14, 2025

Published prices from

$3,699

per person*

taxes & fees included

An aerial view of the bustling city of Balboa, Panama, with a scenic coastal road alongside a marina and tall modern skyscrapers in the background.

FREE All-Inclusive Package Upgrade*+ 1 more offer

Windstar

7-night Costa Rica & Panama Canal Cruise

Golfo Dulce (Puerto Jimenez)

Aboard

Star Pride

From

Colon, Panama

4 Sailings

Dec 13, 2025 - Feb 23, 2026

4 Sailings

Dec 13, 2025 - Feb 23, 2026

A close-up aerial view of the dramatic limestone bluff, known as the "Bluff," a landmark on Cayman Brac island, with waves crashing against its vertical face.

FREE All-Inclusive Package Upgrade*+ 1 more offer

Windstar

19-night Star Collector: Caribbean Cultures: Latin America & the Greater Antilles Cruise

San Andres Island

Aboard

Wind Surf

From

Colon, Panama

1 Sailing

Feb 9, 2026

1 Sailing

Feb 9, 2026

A panoramic view of the bustling harbor of Manzanillo, Mexico, with a large tanker docked and mountains in the background under a bright blue sky.

FREE Champagne, Entertainment, Dining & More*

Windstar

15-night Star Collector: Panama Canal, Costa Rica & Mexican Riviera Discovery Cruise

Golfo Dulce (Puerto Jimenez)

Aboard

Star Seeker

From

Colon, Panama

1 Sailing

Apr 13, 2026

1 Sailing

Apr 13, 2026

An aerial view of the bustling city of Balboa, Panama, with a scenic coastal road alongside a marina and tall modern skyscrapers in the background.

FREE All-Inclusive Package Upgrade*+ 1 more offer

Windstar

10-night Monteverde Cloud Forest & Arenal Volcano Cruise/Land Package

Golfo Dulce (Puerto Jimenez)

Aboard

Star Pride

From

Colon, Panama

1 Sailing

Dec 13, 2025

1 Sailing

Dec 13, 2025

A dramatic sunset over Lake Arenal in Costa Rica, with a majestic, conical Arenal Volcano emitting a plume of smoke and fiery clouds into the orange sky.

FREE All-Inclusive Package Upgrade*+ 1 more offer

Windstar

11-night Monteverde Cloud Forest & Arenal Volcano Cruise/Land Package

Golfo Dulce (Puerto Jimenez)

Aboard

Star Pride

From

Colon, Panama

2 Sailings

Feb 9 - Feb 23, 2026

2 Sailings

Feb 9 - Feb 23, 2026

The ancient stone ruins of a majestic Mayan temple or pyramid, featuring historic architecture at an archaeological site in Mexico's Costa Maya region.

FREE All-Inclusive Package Upgrade*+ 1 more offer

Windstar

8-night Mayan Legacies Cruise

San Andres Island

Aboard

Wind Surf

From

Colon, Panama

1 Sailing

Feb 9, 2026

1 Sailing

Feb 9, 2026

A tranquil beach on Isla Parida, with gentle waves lapping against the sandy shore and a lush green rainforest lining the coast.

FREE Champagne, Entertainment, Dining & More*

Windstar

10-night Monteverde Cloud Forest & Arenal Volcano Cruise/Land Package

Golfo Dulce (Puerto Jimenez)

Aboard

Star Legend

From

Colon, Panama

3 Sailings

Jan 5 - Feb 2, 2027

3 Sailings

Jan 5 - Feb 2, 2027

A dreamy long-exposure shot of the coastline in Manuel Antonio National Park near Quepos, Costa Rica, with a tranquil, misty ocean flowing between large, jagged rocks and a lush green headland in the distance at sunset.

FREE Champagne, Entertainment, Dining & More*

Windstar

7-night Costa Rica & Panama Canal Cruise

Golfo Dulce (Puerto Jimenez)

Aboard

Star Legend

From

Colon, Panama

3 Sailings

Jan 5 - Feb 2, 2027

3 Sailings

Jan 5 - Feb 2, 2027