24 nights South Caribbean From Genoa, Italy

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A scenic view of Catalina Island, Dominican Republic, with a pristine sandy beach lined with palm trees and the calm turquoise waters of the Caribbean Sea in the background.
MSC Opera cruise ship exterior.
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ABOARD

MSC Opera

MSC Opera cruise ship exterior.

Departing

Visiting

Genoa, Italy


13 Ports of Call

Sailing Oct 30, 2026

Your 24-night Africa Cruise at a Glance

Sailings aboard MSC Opera depart from Genoa, Italy with 13 stops in ports-of-call including Philipsburg, St. Maarten, Basseterre, St. Kitts, and Pointe A Pitre. The Cruise Web can help you find the best deals and stateroom prices on the next sailing October 30, 2026.

Departure Port

Genoa, Italy

Genoa is a lively port city with a rich history, narrow streets, cool architecture, and plenty of seafood to enjoy. Before you depart Genoa, Italy, we can help you plan travel and accommodations for your Africa cruise.

Destination

Africa

Stops on your Africa voyage will include Florence/Pisa (Livorno) on day 2 and La Romana on day 18. We can help you with excursions and making the most of any itinerary.

Cruise Ship

MSC Opera

MSC Opera, built in 2004 and refurbished in 2015, carries 2,150 passengers with a crew of 742.

Cruise Line

MSC Cruises

Enjoy Italian luxury and eco-conscious vacationing with MSC Cruises. We can help you maximize deals on Africa cruises aboard MSC Opera or 23 of MSC’s other ships.