22-night South America & Antarctica Cruise From Valparaiso (Santiago), Chile

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A breathtaking action shot of a killer whale breaching from the deep blue Antarctic waters, with a massive glacier and icebergs in the background.
Holland America's Oosterdam sailing in Alaska.
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ABOARD

Oosterdam

4.3

40 reviews

Holland America's Oosterdam sailing in Alaska.

Departing

Visiting

Valparaiso (Santiago), Chile

16 Ports of Call

Sailing Jan 10, 2027

from $5,679 per person* taxes and fees included

Your 22-night South America Cruise at a Glance

Sailings aboard Oosterdam depart from Valparaiso (Santiago), Chile with 16 stops in ports-of-call including Drake Passage, Montevideo, and Buenos Aires. The Cruise Web can help you find the best deals and stateroom prices on the next sailing January 10, 2027.

Departure Port

Valparaiso (Santiago), Chile

Valparaíso is a colorful hillside city on Chile’s coast, known for its bohemian vibe, vibrant street art, and dramatic ocean views. Before you depart Valparaiso (Santiago), Chile, we can help you plan travel and accommodations for your South America cruise.

Destination

South America

Stops on your South America voyage will include Chilean Fjords on day 5 and Alley Glacier on day 8. We can help you with excursions and making the most of any itinerary.

Cruise Ship

Oosterdam

Oosterdam, built in 2003 and refurbished in 2026, carries 1,964 passengers with a crew of 817. Ask us about dining options like Canaletto and entertainment like World Stage!

Cruise Line

Holland America Line

Amazing food and superb service make Holland America one of the longest running cruise lines. We can help you maximize deals on South America cruises aboard Oosterdam or 10 of Holland America’s other ships.