22-night South America & Antarctica Cruise From Buenos Aires, Argentina

Holland America logo

A breathtaking action shot of a killer whale breaching from the deep blue Antarctic waters, with a massive glacier and icebergs in the background.
Holland America's Oosterdam sailing in Alaska.
1 of 2

Sailing Feb 1, 2027

Your 22-night South America Cruise at a Glance

Sailings aboard Oosterdam depart from Buenos Aires, Argentina with 16 stops in ports-of-call including Punta Arenas, Beagle Channel, and Montevideo. The Cruise Web can help you find the best deals and stateroom prices on the next sailing February 1, 2027.

Buenos Aires, the vibrant capital of Argentina, is a city full of energy, rich culture, and European-inspired architecture. Before you depart Buenos Aires, Argentina, we can help you plan travel and accommodations for your South America cruise.

Destination

South America

Stops on your South America voyage will include Puerto Chacabuco on day 20 and Puerto Montt on day 21. We can help you with excursions and making the most of any itinerary.

Cruise Ship

Oosterdam

Oosterdam, built in 2003 and refurbished in 2019, carries 1,964 passengers with a crew of 817. Ask us about dining options like Canaletto and entertainment like BBC Earth Experiences!

Amazing food and superb service make Holland America one of the longest running cruise lines. We can help you maximize deals on South America cruises aboard Oosterdam or 10 of Holland America’s other ships.