16-night Panama Canal Cruise From San Diego, California
Sailing Oct 2, 2026
Your 16-night Mexico Cruise at a Glance
Sailings aboard Nieuw Amsterdam depart from San Diego, California with 11 stops in ports-of-call including Panama Canal, Puerto Vallarta, and Ft. Lauderdale. The Cruise Web can help you find the best deals and stateroom prices on the next sailing October 2, 2026.
Departure Port
San Diego, California
San Diego, California is a sun-soaked coastal city known for its laid-back vibe, scenic beaches, and rich mix of history, culture, and outdoor fun. Before you depart San Diego, California, we can help you plan travel and accommodations for your Mexico cruise.
Destination
Mexico
Stops on your Mexico voyage will include Puerto Vallarta on day 4 and Panama Canal on day 12. We can help you with excursions and making the most of any itinerary.
Cruise Ship
Nieuw Amsterdam
Nieuw Amsterdam, built in 2010 and refurbished in 2019, carries 2,106 passengers with a crew of 929. Ask us about dining options like Morimoto by Sea and entertainment like Cantare!
Cruise Line
Holland America Line
Amazing food and superb service make Holland America one of the longest running cruise lines. We can help you maximize deals on Mexico cruises aboard Nieuw Amsterdam or 10 of Holland America’s other ships.
