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*Rates and offers are per person, in US Dollars, based on double occupancy, capacity controlled, subject to availability and confirmation, and may change without notice. Government taxes and fees are included. Rates and offers are available for select dates and categories only. Additional restrictions may apply. Call 1-800-377-9383 for full terms and conditions.

Amazonas Theatre in Manaus.
Globus

22-Nights South American Odyssey With Amazon & Easter Island

Santiago
Bariloche
Buenos Aires
Manaus (Amazon River)
Easter Island
+4 more

From

Santiago

1 Date

Nov 14, 2025

1 Date

Nov 14, 2025

Published prices from

$11,631

per person*

taxes & fees included

Casa Rosada government building in Buenos Aires.
Globus

21-Nights South American Odyssey With Peru

Santiago
Iguassu Falls (Brazilian Side)
Puerto Varas
Machu Picchu
Lima
+5 more

From

Santiago

1 Date

Nov 18, 2025

1 Date

Nov 18, 2025

Published prices from

$9,815

per person*

taxes & fees included

Amazonas Theatre in Manaus.
Globus

22-Nights South American Odyssey With Amazon & Easter Island

Amazon Jungle
Iguassu Falls (Brazilian Side)
Easter Island
Manaus (Amazon River)
Rio de Janeiro
+4 more

From

Amazon Jungle

5 Dates

Feb 13 - Nov 13, 2026

5 Dates

Feb 13 - Nov 13, 2026

Published prices from

$12,131

per person*

taxes & fees included

A breathtaking panoramic view of the ancient Inca citadel of Machu Picchu, a UNESCO World Heritage site, showcasing its stone structures and terraced fields amid the Andes Mountains in Peru.
Globus

25-Nights South American Odyssey With Amazon & Peru

Santiago
Sacred Valley
Puerto Varas
Machu Picchu
Lima
+7 more

From

Santiago

1 Date

Nov 14, 2025

1 Date

Nov 14, 2025

Published prices from

$11,692

per person*

taxes & fees included

An aerial view of the town of Puerto Varas, Chile, with a prominent red-roofed church in the foreground. The town sits on the shore of a large blue lake, with the snow-capped Osorno Volcano visible in the distance across the water. The sky is bright and clear.
Globus

14-Nights South American Odyssey

Santiago
Buenos Aires
Iguassu Falls (Brazilian Side)
Rio de Janeiro
Puerto Varas

From

Santiago

1 Date

Nov 18, 2025

1 Date

Nov 18, 2025

Published prices from

$7,011

per person*

taxes & fees included

An aerial view of the town of Puerto Varas, Chile, with a prominent red-roofed church in the foreground. The town sits on the shore of a large blue lake, with the snow-capped Osorno Volcano visible in the distance across the water. The sky is bright and clear.
Globus

18-Nights South American Odyssey With Amazon

Puerto Varas
Rio de Janeiro
Santiago
Manaus (Amazon River)
Buenos Aires
+3 more

From

Puerto Varas

8 Dates

Jan 23 - Nov 13, 2026

8 Dates

Jan 23 - Nov 13, 2026

Published prices from

$9,094

per person*

taxes & fees included

An aerial view of Bariloche, Argentina, showing the prominent stone Catedral de San Carlos de Bariloche with its tall spire. The church is situated on the shore of the deep blue Nahuel Huapi Lake, which stretches toward a distant range of hazy mountains.
Globus

18-Nights South American Odyssey With Amazon

Santiago
Amazon Jungle
Puerto Varas
Iguassu Falls (Brazilian Side)
Manaus (Amazon River)
+3 more

From

Santiago

1 Date

Nov 14, 2025

1 Date

Nov 14, 2025

Published prices from

$8,907

per person*

taxes & fees included

A powerful view of the majestic Iguassu Falls on the Brazilian side, with massive cascades of water, lush green foliage on the rocks, and a vibrant blue sky.
Globus

25-Nights South American Odyssey With Amazon & Peru

Lima
Santiago
Buenos Aires
Manaus (Amazon River)
Rio de Janeiro
+7 more

From

Lima

7 Dates

Jan 23 - Nov 13, 2026

7 Dates

Jan 23 - Nov 13, 2026

Published prices from

$12,017

per person*

taxes & fees included

An aerial view of the town of Puerto Varas, Chile, with a prominent red-roofed church in the foreground. The town sits on the shore of a large blue lake, with the snow-capped Osorno Volcano visible in the distance across the water. The sky is bright and clear.
Globus

14-Nights South American Odyssey

Buenos Aires
Rio de Janeiro
Puerto Varas
Bariloche
Iguassu Falls (Brazilian Side)

From

Buenos Aires

9 Dates

Jan 27 - Nov 17, 2026

9 Dates

Jan 27 - Nov 17, 2026

Published prices from

$6,912

per person*

taxes & fees included

The ornate Baroque bell towers and domes of a historic stone cathedral in Cuzco, Peru, set against a bright blue sky with clouds.
Globus

21-Nights South American Odyssey With Peru

Puerto Varas
Machu Picchu
Santiago
Lima
Buenos Aires
+5 more

From

Puerto Varas

8 Dates

Jan 27 - Oct 6, 2026

8 Dates

Jan 27 - Oct 6, 2026

Published prices from

$9,845

per person*

taxes & fees included

An aerial panoramic view of the modern Santiago cityscape, with the Mapocho River flowing through it and the impressive Gran Torre Santiago skyscraper towering over the buildings, all set against the backdrop of the Andes Mountains.
Globus

18-Nights South American Odyssey With Easter Island

Puerto Varas
Bariloche
Iguassu Falls (Brazilian Side)
Buenos Aires
Santiago
+2 more

From

Puerto Varas

4 Dates

Apr 21 - Sep 15, 2026

4 Dates

Apr 21 - Sep 15, 2026

Published prices from

$10,279

per person*

taxes & fees included