4-night Catalina & Ensenada Cruise From San Diego, California

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A scenic view of Catalina Island, Dominican Republic, with a pristine sandy beach lined with palm trees and the calm turquoise waters of the Caribbean Sea in the background.
Royal Caribbean Serenade of the Seas ship exterior
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Sailing Oct 11, 2026 - Apr 18, 2027

from $307 per person* taxes and fees included

Your 4-night Mexico Cruise at a Glance

Sailings aboard Serenade of the Seas depart from San Diego, California with 2 stops in ports-of-call including Catalina Island and Ensenada. The Cruise Web can help you find the best deals and stateroom prices on any of the 15 upcoming sailings in 2026 and 2027.

Departure Port

San Diego, California

San Diego, California is a sun-soaked coastal city known for its laid-back vibe, scenic beaches, and rich mix of history, culture, and outdoor fun. Before you depart San Diego, California, we can help you plan travel and accommodations for your Mexico cruise.

Destination

Mexico

Stops on your Mexico voyage will include Catalina Island on day 2 and Ensenada on day 3. We can help you with excursions and making the most of any itinerary.

Serenade of the Seas, built in 2003 and refurbished in 2022, carries 2,143 passengers with a crew of 832. Ask us about dining options like Windjammer and entertainment like Original Productions!

Royal Caribbean International is known for ships with a wow factor. From ice skating rinks to zip lines, if you can think of it, you can find it on a Royal Caribbean cruise. We can help you maximize deals on Mexico cruises aboard Serenade of the Seas or 30 of Royal Caribbean’s other ships.