16-night Pearls, Palapas & Panama Cruise From Los Angeles, California

Regent Seven Seas Cruises.

A wide-angle landscape shot of the three iconic volcanoes, Agua, Fuego, and Acatenango, in Guatemala, rising above the clouds during a vibrant sunrise, a scenic view near Puerto Quetzal.
Regent Seven Seas Prestige Cruise Ship exterior.
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Sailing Mar 5, 2029

from $11,799 per person* taxes and fees included

Your 16-night Caribbean Cruise at a Glance

Sailings aboard Seven Seas Prestige depart from Los Angeles, California with 9 stops in ports-of-call including Miami, Grand Cayman (George Town), and Cabo San Lucas. The Cruise Web can help you find the best deals and stateroom prices on the next sailing March 5, 2029.

Los Angeles is a sprawling, star-studded city where beach culture, global cuisine, and Hollywood glamour meet laid-back California cool. Before you depart Los Angeles, California, we can help you plan travel and accommodations for your Caribbean cruise.

Destination

Caribbean

Stops on your Caribbean voyage will include Cabo San Lucas on day 4 and Grand Cayman (George Town) on day 15. We can help you with excursions and making the most of any itinerary.

Seven Seas Prestige, built in 2026, carries 822 passengers with a crew of 630.

Offering a completely all-inclusive cruise, Regent Seven Seas is known for exquisite service on beautifully designed intimate ships, classic cruising at its best. We can help you maximize deals on Caribbean cruises aboard Seven Seas Prestige or 6 of Regent’s other ships.