16-night Panama Canal & Pacific Gems Cruise From Miami, Florida

Regent Seven Seas Cruises.

A scenic shot of the stunning Seven Mile Beach in Grand Cayman, with a wide, sandy beach, calm turquoise water, and resorts with palm trees under a beautiful blue sky.
Regent Seven Seas Grandeur cruise ship exterior
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Sailing Dec 29, 2026

from $14,349 per person* taxes and fees included

Your 16-night Caribbean Cruise at a Glance

Sailings aboard Seven Seas Grandeur depart from Miami, Florida with 10 stops in ports-of-call including Puerto Quetzal, Acapulco, and Florida Strait. The Cruise Web can help you find the best deals and stateroom prices on the next sailing December 29, 2026.

Departure Port

Miami, Florida

Miami is a sun-soaked city that blends beach life, global flavors, and bold style into one vibrant, nonstop experience. Before you depart Miami, Florida, we can help you plan travel and accommodations for your Caribbean cruise.

Destination

Caribbean

Stops on your Caribbean voyage will include Cartagena (Colombia) on day 5 and Panama Canal on day 6. We can help you with excursions and making the most of any itinerary.

Seven Seas Grandeur, built in 2020, carries 744 passengers with a crew of 548. Ask us about dining options like Chartreuse and entertainment like Card Room!

Offering a completely all-inclusive cruise, Regent Seven Seas is known for exquisite service on beautifully designed intimate ships, classic cruising at its best. We can help you maximize deals on Caribbean cruises aboard Seven Seas Grandeur or 6 of Regent’s other ships.