7-night Wonders Of Colombia With 3-nights In Medellín, 2-nights In Cartagena Pre Cruise And 3-nights In Panama City Post Cruise From Medellín, Colombia

AmaWaterways' Logo.

A beautiful colonial-era church in Mompox, Colombia, with its vibrant yellow facade, ornate bell tower, and bright red dome standing out against a clear blue sky.
Amawaterways AmaMelodia river ship exterior.
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Sailing Feb 19 - Dec 10, 2027

Your 15-night Mexico Cruise at a Glance

Sailings aboard AmaMelodia depart from Medellín, Colombia with 8 stops in ports-of-call including Barranquilla, Santa Barbara de Pinto, and Cartagena (Colombia). The Cruise Web can help you find the best deals and stateroom prices on any of the 10 upcoming sailings in 2027.

Departure Port

Medellín, Colombia

Medellín is a dynamic, hillside city that’s transformed itself into one of South America’s most innovative and inviting urban centers. Before you depart Medellín, Colombia, we can help you plan travel and accommodations for your Mexico cruise.

Destination

Mexico

Stops on your Mexico voyage will include Cartagena (Colombia) on day 4 and Calamar on day 7. We can help you with excursions and making the most of any itinerary.

Cruise Ship

AmaMelodia

AmaMelodia, built in 2024, carries 64 passengers with a crew of 30.

Cruise Line

AmaWaterways

Explore the world’s most beautiful rivers, creating a lifetime of memories from AmaWaterways’ intimate, luxurious river ships. We can help you maximize deals on Mexico cruises aboard AmaMelodia or 34 of AmaWaterways’s other ships.